Asbestos related pleural malignant mesothelioma-18F-FDG PET/CT findings-

石棉相关胸膜恶性间皮瘤-18F-FDG PET/CT结果-

• 批准号: 19591440
• 负责人: KURATA Seiji
• 金额: $ 2.75万
• 依托单位: Kurume University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19591440/
• 关键词: PET; CT; アスベスト; 悪性胸膜中皮腫; 画像診断学; 悪陸胸膜中皮腫

Analysis of 18F-FDG PET/CT and plasma osteopontin levels were performed in asbestos-related pleural disease patients. Six patients had histologically proven malignant pleural mesothelioma (MPM). In 11 patients, the disease was considered benign pleural disease. Four patients had proven asbestos pleurisy. The remaining 7 patients had proven pleural plaques. Significant differences were found among the three groups of asbestos-related pleural diseases for the plasma osteopontin levels and the SUVmax. Significant differences in the SUVmax were found between patients with MPM and those with asbestos pleurisy and between patients with MPM and patients with pleural plaques. However, there was no significant difference in the plasma osteopontin levels between patients with MPM and patients with asbestos pleurisy or between patients with MPM and patients with pleural plaques. The SUVmax in patients with benign asbestos-related diseases correlated well with plasma osteopontin levels in the same group, but the SUVmax in patients with MPM did not correlate with plasma osteopontin levels in the same group. PET/CT might be more helpful in distinguishing benign asbestos-related pleural diseases from MPM than plasma osteopontin, and the SUVmax in benign asbestos-related pleural diseases may reflect changes in pleural inflammation.

对石棉相关性胸膜疾病患者进行18F-FDG PET/CT和血浆骨桥蛋白水平分析。6例经病理证实为恶性胸膜间皮瘤。在11例患者中，该疾病被认为是良性胸膜疾病。4例患者证实为石棉性胸膜炎。其余7例患者证实有胸膜斑块。三组石棉相关性胸膜疾病患者血浆骨桥蛋白水平和SUVmax差异有统计学意义。MPM患者与石棉性胸膜炎患者之间以及MPM患者与胸膜斑块患者之间的SUVmax存在显著差异。但是，MPM患者与石棉性胸膜炎患者之间或MPM患者与胸膜斑块患者之间的血浆骨桥蛋白水平无显著差异。良性石棉相关疾病患者的SUVmax与同组血浆骨桥蛋白水平相关性良好，但MPM患者的SUVmax与同组血浆骨桥蛋白水平不相关。PET/CT可能比血浆骨桥蛋白更有助于区分良性石棉相关性胸膜疾病与MPM，并且良性石棉相关性胸膜疾病的SUVmax可能反映胸膜炎症的变化。

项目成果

Improved breast cancer detection of prone breast fluorodeoxyglucose-PET in 118 patients Nuclear Medicine Communications

氟脱氧葡萄糖-PET 在 118 名患者中改进了乳腺癌检测核医学通讯

• 发表时间: 2008
• 期刊: 29(10)
• 作者: Hayato Kaida;Masatoshi Ishibashi;Teruhiko Fujii;Seiji Kurata;Masafumi Uchida;Kenkichi Baba;Teruo Miyagawa;Hiroko Kaibara;Seiji Kawamura;Etsuyo Ogo;Naofumi Hayabuchi.
• 通讯作者: Naofumi Hayabuchi.

Preliminary study of PET/CT and plasma osteopontin levels in patients with asbestos-related pleural disease Jpn J Radiol

石棉相关性胸膜病患者PET/CT及血浆骨桥蛋白水平的初步研究 Jpn J Radiol

• 发表时间: 2010
• 期刊: (in press)
• 作者: Seiji Kurata;Masatoshi Ishibashi;Koichi Azuma;Hayato Kaida;Shinzo Takamori;Kiminori Fujimoto;Maiko Kobayashi;Yasumitsu Hirose;Hisamichi Aizawa;Naofumi Hayabuchi
• 通讯作者: Naofumi Hayabuchi

Prognostic value of SUVmax measurements obtained by FDG-PET in patients with non-small cell lung cancer receiving chemotherapy

• DOI: 10.1016/j.lungcan.2010.04.004
• 发表时间: 2011-01-01
• 期刊: LUNG CANCER
• 影响因子: 5.3
• 作者: Imamura, Yohei;Azuma, Koichi;Aizawa, Hisamichi
• 通讯作者: Aizawa, Hisamichi

Masatoshi Ishibashi Mastopathic-type fibroadenoma and ductal adenoma of the breast with false-positive flurodeoxyglucose positron emission tomography Jpn J Radiol

Masatoshi Ishibashi 乳腺病型纤维腺瘤和导管腺瘤伴氟脱氧葡萄糖正电子发射断层扫描假阳性 Jpn J Radiol

• 发表时间: 2009
• 期刊: 27
• 作者: Rin Yamaguchi;Yasuhiko Futamata;Fumihiro Yoshimura;Naotaka Murakami;Kikuo Koufuji;Rumiko Kutani;Kazuyuki Kojima;Shino Ohki;Seiji Kurata;Hayato Kaida
• 通讯作者: Hayato Kaida

Diffuse or combined uptake in the thyroid gland as an incidental finding in FDG-PET

FDG-PET 中偶然发现甲状腺的弥漫性或联合摄取

• 发表时间: 2007
• 作者: Seiji Kurata;Masatoshi Ishibashi;Hayato Kaida;Yuji Hiromatsu;Ikuyo Miyake;Naofumi Hayabuchi.
• 通讯作者: Naofumi Hayabuchi.