頭頸部癌の病期診断における造影PET/CTの有用性の検討

对比增强 PET/CT 在头颈癌分期诊断中的实用性检验

• 批准号: 19790888
• 负责人: 鈴木 晶子
• 金额: $ 1.51万
• 依托单位: Yokohama City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19790888/
• 关键词: 医療・福祉; 癌; 臨床; 放射線

平成19～20年度は頭頚部癌の病期診断における造影PET/CTの有用性を検討し、論文発表した。頭頚部癌では頚部リンパ節転移の有無が治療方針に大きく影響するため、平成21年度はPET/CTによる頚部リンパ節の診断能、特に読影者間の変動(inter-observer variation)と読影者内の変動(intra-observer variation)を検討した。臨床的に頭頚部癌が疑われ、生検(もしくは手術)によって組織学的確定診断の得られた治療前症例(32例)に対して、PET/CTおよび頚部造影CTを施行した。頚部画像について、単純PET/CT画像(PET・単純CT・単純PET/CT融合画像)、造影CT画像、造影PET/CT画像(PET・造影PET/CT融合画像)を画像診断医が読影し、頚部リンパ節転移を評価した。手術適応がある症例は、最終検査後2週間以内に手術が施行された。手術症例では頚部リンパ節の病理診断を確定し、手術症例以外では少なくとも6ヶ月の臨床経過観察と画像診断による経過観察をもって確定診断とした。4名の読影医(専門医2名と非専門医2名)がそれぞれの画像を2回読影した結果を、PET/CTと造影CTとで比較すると、PET/CTの方がinter-observer variationとintra-observer variationが小さい、すなわちどの読影医が診断しても結果が一致する傾向がみられた。診断結果が一致するということは、PET/CTの診断基準が明確で評価方法として優れていることを示唆する。頭頚部癌の病期診断におけるPET/CTの有用性をさらに裏付ける結果となった。

In Pingcheng in 1920, the disease stage of cancer was cut off, the usefulness of radiography PET/CT, and the table of articles were reported. In the cancer department of the cancer department, there is a medical treatment prescription for the treatment of the disease, and in the year 21 of the PET/CT, the power is cut off, and the inter-observer variation (inter-operator training) and the internal training (intra-observer variation) are performed. The confirmed diagnosis of histology in the patients with suspected cancer and surgical treatment was confirmed. 32 cases were diagnosed as having prodromal symptoms, and CT examinations were performed in PET/CT patients. The PET/CT portrait (PET CT fusion portrait), the CT portrait, the PET/CT portrait (PET PET/CT fusion portrait), the portrait of the doctor, the shadow of the doctor, and the image of the doctor. Manual surgery should be performed within 2 years after the most effective treatment. In the case of hand surgery, the pathological diagnosis was confirmed, and in addition to the case of hand surgery, it was confirmed by the observation of the portrait in the six-month-old bed. There were 4 shadow doctors (2 non-medical doctors). The results showed that the results of PET/CT imaging CT images were compared, that of PET/CT images were compared with that of inter-observer variation images, and that the results were consistent. The results showed that the results were consistent with each other, and the basic level of PET/CT test clearly demonstrated that the method was instigated. During the period of illness, the patients with partial cancer were cut off and PET/CT was useful. the results showed that the results were not satisfactory.

项目成果

Adequate usage of intravenous contrast material in head and neck PET/CT study

头颈PET/CT研究中静脉造影剂的充分使用

• 发表时间: 2007
• 作者: Shimahara T;Ito Y;Ariyoshhi Y;Kimura Y;Shimahara M;Kawabata S;Kasaoka S;Ono K and Miyatake S.;Atsushi Doi;吉田啓介;鈴木晶子;鈴木 晶子;鈴木 晶子
• 通讯作者: 鈴木 晶子

Paranasal Sinus Imaging Virtual Visualization for Endoscopic Sinus Surgery

内窥镜鼻窦手术的鼻旁窦成像虚拟可视化

• 发表时间: 2008
• 作者: Shimahara T;Ito Y;Ariyoshhi Y;Kimura Y;Shimahara M;Kawabata S;Kasaoka S;Ono K and Miyatake S.;Atsushi Doi;吉田啓介;鈴木晶子
• 通讯作者: 鈴木晶子

Adrenal gland lesions in cancer patients:advantage and pitfalls in inte rpretation of intravenous contrast enhanced PET/CT

癌症患者的肾上腺病变:静脉造影增强PET/CT解释的优点和缺陷

• 发表时间: 2007
• 作者: Shimahara T;Ito Y;Ariyoshhi Y;Kimura Y;Shimahara M;Kawabata S;Kasaoka S;Ono K and Miyatake S.;Atsushi Doi;吉田啓介;鈴木晶子;鈴木 晶子
• 通讯作者: 鈴木 晶子

Staging primary head and neck cancers with 18F-FDG PET/CT: is intravenous contrast administration really necessary?

• DOI: 10.1007/s00259-009-1127-8
• 发表时间: 2009-09-01
• 期刊: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
• 影响因子: 9.1
• 作者: Yoshida, Keisuke;Suzuki, Akiko;Inoue, Tomio
• 通讯作者: Inoue, Tomio