A Study about the Protection of Functional Deterioration of Deglutition Decline with the Aging by the Hypopharyngeal Constrictor Muscle dosage of IGF-1

我们研究IGF-1对吞咽功能减退的保护作用。本研究利用扫描电镜对大鼠咽下肌亚神经装置（SNA）的衰老效应进行了组织学研究。在环咽肌中，原发性突触裂的凹陷型占63.4%，而IGF-1剂量组占60%。与老年组相比，IGF-1剂量老化组出现了未成熟的神经系统底装置。此外，约27%的小鼠能够观察到神经系统底部的装置，即从初级突触的沟槽向外观察到次级突触。

We studied about the protection of functional deterioration of deglutition decline by IGF-1. In the present study, aging effects in the subneural apparatus (SNA) were histologically investigated in the inferior pharyngeal muscle of a rat using scanning electron microscopy. In the cricopharyngeal muscle, the depression type of the primary synaptic clefts were 63.4%, while the IGF-1 dosage group were 60%. There was more it than aging group, and an unripe nervous system bottom device appeared in the group of IGF-1 dosage aging in comparison with the aging group. In addition, about 27% were able to observe the nervous system bottom device that a secondary synapse was observed outward from the ditch of the primary synapse.