Basic research on analyzes influence of biological apatite crystal gives Osseointegration.

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The purpose of this study was to investigate changes in bone quality associated with the mineralization of new bone forming around implants. This study investigated the quality and composition of new bone that formed around implants at 4 and 8 weeks post-implantation, compared to those of cortical bone. In new bone near cortical bone, PO_4^<3->, CO_3^<2->, and amide I distributions increased over time, and calcification progressed. In new bone more distant from cortical bone, PO_4^<3->, CO_3^<2->, and amide I distributions also increased over time, but to a lesser extent compared to that close to cortical bone. Our findings clearly showed changes in bone quality related to the degree of mineralization, based on sequential changes in chemical bonding and the distribution of elements and molecules comprising bone.