Fundamental researches of the histologic estimate using morphologic changes of bronchioloalveolar carcinoma between inspiratory and expiratory CT

细支气管肺泡癌吸气与呼气CT形态学变化评估组织学的基础研究

• 批准号: 22659223
• 负责人: NAKADA Hiroshi
• 金额: $ 0.74万
• 依托单位: University of Miyazaki
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Challenging Exploratory Research
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22659223/
• 关键词: 癌; 放射線

A trial to exclude Noguchi classification type C that can cause lymph node metastases is considered in the bronchioloalveolar carcinoma(following BAC) with the ground glass opacity by CT, but there is it in the situation that is hard to say to have established it enough. We paid our attention to the structure that was a rough work of BAC in this study and hypothesized that grade of BAC was high as a "firm" tumor and expressed "hardness" by measuring a diameter rate of change, absorption level rate of change by inspiratory and expiratory CT and tried a grade analogy of BAC based on the results.The significant difference was not obtained at all at results, however, a constant tendency was found between Noguchi classification type B vs. type C. Therefore, likelihood of the extraction of the Noguchi classification type C which is clinically important was shown by using inspiratory and expiratory CT.

在CT显示毛玻璃样阴影的细支气管肺泡癌（BAC后）中，考虑进行排除可能导致淋巴结转移的Noguchi分类C型的试验，但在很难说已经充分确定的情况下，也存在这种试验。在本研究中，我们关注BAC的粗糙结构，并假设BAC的等级高为“坚固”肿瘤，并通过吸气和呼气CT测量直径变化率、吸收水平变化率来表示“硬度”，并根据结果尝试BAC的等级类比。结果完全没有获得显著差异，但是，在Noguchi分类B型与C型之间发现恒定的趋势。因此，通过使用吸气和呼气CT显示了提取具有临床重要性的Noguchi分类C型的可能性。