A Research of pleasant sounds those bring human relaxation, based on the neural mechanism of instinct.

基于本能的神经机制研究带来人类放松的悦耳声音。

• 批准号: 19700201
• 负责人: SHUTOH Fumihiro
• 金额: $ 2.36万
• 依托单位: University of Tsukuba
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19700201/
• 关键词: 感性脳科学; 感性官能評価; 脳機能; 聴覚; 本能; 情動; 近赤外光; 音; 音楽; NIRS; 光トポグラフィー; 神経伝達物質; セロトニン; モノアミン; 神経

I explored the attractive sounds for human, and physical effects of those attractive auditory stimulations were examined in both of the human and the mouse. Human examinees were exposed a sequence of auditory stimulation which are composed of several kinds of sound (ex. watch, wavelets, music) and white noise. Some of these sounds were judged as attractive by the examinees in an interview study. A near infrared spectroscopic study revealed that the activity of the frontal cortex were stable during the attractive sound stimulation. I kept mice in a box that controlled sound and light condition. The mice were exposed twelve hours (20:00-8:00) of the attractive sound stimulation for a week. After the sound exposing period, the mice were sacrificed and monoamine concentration in their brain was measured by high performance liquid chromatography. Concentration of serotonin in the frontal brain region of the sound exposed mice was higher than the mice kept in silent. These results suggest that serotonergic system can be involved in the attractive physical effects of sounds.

本研究探索了人类所能听到的具有吸引力的声音，并在人类和小鼠中检验了这些具有吸引力的听觉刺激的物理效应。人类受试者暴露于由几种声音组成的听觉刺激序列（例如，手表、小波、音乐）和白色噪声。其中一些声音在面试中被考生认为是有吸引力的。近红外光谱研究表明，在吸引声刺激期间，额叶皮层的活动是稳定的。我把老鼠关在一个能控制声音和光线的盒子里。将小鼠暴露于12小时（20：00-8：00）的有吸引力的声音刺激一周。暴露后处死小鼠，用高效液相色谱法测定脑内单胺含量。声音暴露组小鼠额叶脑区5-羟色胺浓度高于安静组。这些结果表明，多巴胺能系统可能参与声音的吸引力物理效应。

项目成果

音刺激がヒトとマウスの脳活動に与える効果

声音刺激对人类和小鼠大脑活动的影响

• 发表时间: 2008
• 作者: 首藤文洋;ほか7名
• 通讯作者: ほか7名

Environmental Auditory Stimulation Affects Brain Activity in the Human Cerebral Cortex and the Mouse Brain.

环境听觉刺激会影响人类大脑皮层和小鼠大脑的大脑活动。

• 发表时间: 2009
• 作者: Shutoh Fumihiro;Okubo Marie;Mizutani Nanami;Nakamori Shiho;Ohshima Naoki;Uchiyama Toshiaki;Yamanaka Toshimasa;Hisano Setuji
• 通讯作者: Hisano Setuji

「本能」をベースに醸し出される感性の脳機能-被験者実験と動物実験の相関から見えてくるもの

基于“本能”的情绪脑功能——从人体实验与动物实验的相关性可以看出什么

• 发表时间: 2009
• 作者: 神里志穂子;野口健太郎;比嘉信;山田孝治;首藤文洋;首藤文洋
• 通讯作者: 首藤文洋

For designing, do you need the users' Kansei information based on brain science?

设计时，是否需要用户基于脑科学的感性信息？

• 发表时间: 2008
• 作者: Shutoh Fumihiro;Okubo Marie;Mizutani Nanami;Nakamori Shiho;Ohshima Naoki;Uchiyama Toshiaki;Yamanaka Toshimasa;Hisano Setuji;Fumihiro Shutoh;Fumihiro Shutoh;Fumihiro Shutoh
• 通讯作者: Fumihiro Shutoh

Environmental auditory stimulation affects brain activity in the human cerebral cortex and the mouse brain

环境听觉刺激影响人类大脑皮层和小鼠大脑的大脑活动

• 发表时间: 2009
• 作者: 首藤文洋;ほか7名
• 通讯作者: ほか7名