Preventive effect of sesaminol on life style-related disease

芝麻素酚对生活方式相关疾病的预防作用

• 批准号: 19700590
• 负责人: NISHIZONO Shoko
• 金额: $ 3.38万
• 依托单位: University of Miyazaki
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19700590/
• 关键词: ゴマリグナン; セサミノール配糖体; 脂質代謝; トコフェロール; セサミノール; コレステロール合成; ステロイド排泄; セサミノールグルコシド; 排泄率; 血清コレステロール

Sesaminol is a lignan with beneficial physiological activities derived from sesame. Effects of sesaminol triglycoside on lipid metabolism were investigated in rats. Sessaminol triglycoside was extracted from defatted sesame seed. Sesaminol triglycoside did not affect on serum and liver lipid levels, while sesamin decreased serum triglyceride level. d-Tocopherol contents in the liver were higher in sesaminol and sesamin groups compared to control group. These results suggest that sesaminol triglycoside exerts antioxidative activity as sesamin.

芝麻胺醇是一种从芝麻中提取的具有有益生理活性的木脂素。研究了芝麻酚三苷对大鼠脂质代谢的影响。从脱脂芝麻中提取芝麻酚三糖苷。芝麻素对血清和肝脏脂质水平无影响，而芝麻素可降低血清甘油三酯水平。与对照组相比，芝麻胺醇和芝麻素组肝脏中d-生育酚含量较高。这些结果表明，芝麻酚三糖苷发挥抗氧化活性的芝麻素。

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