Diversity of sex-related mortality and outcome in preterm infants and neonates (S02)

早产儿和新生儿性别相关死亡率和结局的多样性（S02）

• 批准号: 536611726
• 金额: --
• 依托单位: Institut für Medizinische Biometrie und Statistik
• 依托单位国家: 德国
• 项目类别: Collaborative Research Centres
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/536611726?language=en
• 关键词: Diversity; sex; related; mortality; outcome

The project will develop polygenic scores predictive for steroid hormones after birth. Thus, instead of adopting an essentialising binarism, the project will operationalise the concept of “sex diversity” as genetically related steroid hormone levels. Through the existing German Neonatal Network (GNN), blood samples will be drawn in the first 48 hours of life and, in collaboration with M06 and their service unit for steroid measurements, a hormonal profile will be established and the respective polygenic scores calculated.

该项目将开发多基因评分预测出生后的类固醇激素。因此，该项目将把“性别多样性”的概念作为与遗传相关的类固醇激素水平，而不是采用本质上的二元论。通过现有的德国新生儿网络（GNN），将在出生后的前48小时内抽取血液样本，并与M06及其服务单位合作进行类固醇测量，建立激素谱并计算相应的多基因评分。