Measurement and Numerical Modeling of the Characteristics of Red Blood Cell Suspended in Fluid Under Uniform Magnetic Field

本研究开发了一种利用高速摄像机、微通道、微电子传感器测量强磁场下悬浮在液体中的单个红细胞的磁电特性的实验技术。在此基础上，提出了一种利用荧光偏振法测量微通道内流体温度的新方法。利用这些测量技术，可以分析0-10特斯拉磁场下红细胞在流体中的运动。进一步利用测量数据建立了可以直接模拟磁效应对红细胞膜物理影响的数值模型。该模型具有较强的通用性，可用于生物数值模拟器中红细胞在流体中的三维运动。

Experimental technology that can measure the magnetic and electric characteristics of a single red blood cell (RBC) suspended in a fluid exposed under strong magnetic field using high-speed camera, microchannels, micro-electric sensors was developed in this study. Further, a novel fluid temperature measurement in microchannels using fluorescent polarization method was also developed. By using these measurement technologies, the RBC motions in fluids under magnetic field of 0-10 Tesla could be analyzed. The measurement data was further used to develop a numerical model that can directly simulate the physics of the magnetic effect on the RBC membrane. This model possesses a high general versatility to simulate three-dimensional RBC motion in fluids and can be applied to a biologic numerical simulator.