Volitional control over working memory neurons in monkey prefrontal cortex with biofeedback technique

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To understand how nervous system represents intention and volition, we recorded single unit activity of neurons in the monkey lateral prefrontal cortex while monkeys performed delayed matching tasks. Also animal subjects could successfully make volitional control on the activity of prefrontal neurons according to task requirements during the tasks by the biofeedback technique. Results provide an important knowledge on neural codes of intention and volition, which leads to future techniques on the cognitive BMI.