Study on functionalization of biomaterials by controlling the high order structure

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The size of the receptor on the cellular membrane and the recognition of the adhesion molecules are regulated in nanometer order. Therefore it is necessary to design and to control the 3D structure of the materials. In this consequence, we try to understand the real cell recognition mechanism on the functionalized biomaterials by controlling the material nano-micro-macro structure. In this research, we aimed (1) "control of the second/three-dimensional array structure of the fiber" and (2) "three-dimensional structural control of the concentrated polymer brush", and the bodily function characteristic was examined in detail. From the results, the concept of the new type of the tissue engineering scaffolds was developed.