Photoaffinity capture for the identification of functional site within proteins of nano-mol amount

近年来，随着药物开发的不断深入，计算机辅助设计新药成为可能，这些新药通常被称为“分子靶向药物”。“目前的研究开发了几种新型的光活化探针，可有效用于分析痕量蛋白质。该方法成功地解决了代谢酶的重要结合位点。

Recent progress in the drug developments enables the computer aided design of new medicines which are often called as "molecular target drugs." The present research developed several novel photo-activatable probes that are effective for the analysis trace amount proteins. The application of this purobe was successful for solving important binding-site within a metabolic enzyme.