Evaluation of relationships between root resorption accompanied with orthodontic tooth movement and cell death of cementum-related cells

本研究旨在阐明正畸牙移动引起牙根吸收的生物学机制。以8周龄Wistar大鼠为实验动物模型。用悬臂式镍钛合金丝弓将单侧第一磨牙向颊移动。直径012寸)。初始力调整为20gf。结果表明，随着正畸牙的移动，脱细胞牙骨质的成牙本质细胞死亡可引起破牙细胞的吸收活动，提示成牙骨质细胞的死亡与牙根吸收有关。

The purpose of this study was to clarify the biological mechanism of root resorption caused by orthodontic tooth movement. 8-week-old Wistar rats were used as an experimental animal model. The unilateral first molar was moved buccaly by a cantilever-type Ni-Ti wire(. 012 inch in diameter). The initial force was adjusted to 20 gf. The results indicate that cell death of cementoblasts of acellular cementum accompanied by orthodontic tooth movement may induce resorptive activities of odontoclasts, which suggest relationship between cell death of cementoblasts and root resorption.