Excitatory and Inhibitory synapse distribution on cortical neurons

了解大脑的电路结构对阐明其功能至关重要。近年来，皮层回路的抑制成分受到越来越多的关注。尽管兴奋性突触输入在皮层非锥体细胞亚型中分布密度不同，但我们发现不同亚型的皮质非锥体细胞之间GABA阳性突触密度无显著差异。我们还发现兴奋性丘脑-皮层传入纤维很少被皮层小白蛋白阳性细胞树突支配，而皮层内传入纤维则被丰富地支配。

Understanding the brain's circuit architecture is critical to elucidating its function. Recently, the inhibitory components of cortical circuits have received increased attention. We have found no significant difference of the GABA positive synapse density among different subtype of cortical nonpyramidal cells, although excitatory synapse inputs are found to distribute in different density among cortical nonpyramidal cell subtypes. We also found that excitatory thalamo-cortical afferent fibers are rarely innervated cortical parvalbumin positive cell dendrites and intra-cortical afferent fibers are richly innervated them.