The setting of proper exercise load used activation in satellite cell and expression of MyoD family in skeletal muscle as index.

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We thought that the setting of proper exercise load used activation in satellite cell and expression of MyoD family in skeletal muscle as index was clinically effective. After research on the activation threshold of satellite cells and expression of MyoD family in normal muscle, we analyzed the difference between atrophy and normal muscle. From the viewpoint of physical therapy, we considered optimal intervention condition in atrophy muscle from comparison analysis in weight-bearing and gait. It was thought that combination of the use of the activation threshold and pathological observation was important to the setting of proper exercise load that avoided muscle damage by excessive load.