Epidemiological and clinicopathological study of chronic kidney disease and metabolic syndrome related kidney injury

慢性肾脏病及代谢综合征相关肾损伤的流行病学及临床病理学研究

• 批准号: 20500614
• 负责人: UENO Mitsuhiro
• 金额: $ 2.41万
• 依托单位: Joetsu University of Education
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20500614/
• 关键词: 慢性腎臓病; メタボリックシンドローム; 疫学; 内科; 病理学

This study aimed to reveal the relationship between metabolic syndrome (MS) and chronic kidney disease (CKD). Health-check data of the MS group and the non-MS group were compared. The MS group contained significantly more CKD patients than the non-MS group. Both urinary albumin excretion rate and the level of proteinuria in the MS group were significantly higher than that in the non-MS group, and the renal function of the former was significantly lower than that of the latter. The MS-specific nephropathy may exist since the MS group included more patients with microalbuminuria and proteinuria than the non-MS group, even if excluding the patients with past history of hypertension and diabetes mellitus.

本研究旨在揭示代谢综合征（MS）与慢性肾脏病（CKD）的关系。比较MS组和非MS组的健康检查数据。MS组的CKD患者明显多于非MS组。MS组尿白蛋白排泄率和尿蛋白水平均显著高于非MS组，肾功能显著低于非MS组。即使排除既往有高血压和糖尿病史的患者，MS组中微量白蛋白尿和蛋白尿的患者也多于非MS组，因此可能存在MS特异性肾病。

项目成果

カラー版メディカルノート 腎臓がわかる. 腎・尿路疾患/水・電解質代謝異常

彩色版医学笔记：了解肾脏/泌尿道疾病/水/电解质代谢紊乱。

• 发表时间: 2008
• 作者: 上野光博;下条文武
• 通讯作者: 下条文武

自己免疫性膵炎の治療後、腎機能障害が進行したIgG4関連間質性腎炎の一例

自身免疫性胰腺炎治疗后出现IgG4相关间质性肾炎伴进行性肾功能障碍1例

• 发表时间: 2008
• 作者: 才田優;上野光博;他5名
• 通讯作者: 他5名