Study on the prolactin receptors and there signal transduction in fish erythrophores and xanthophores.
Study on the prolactin receptors and there signal transduction in fish erythrophores and xanthophores.
批准号:
20570076
负责人:
OSHIMA Noriko
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We found that a pituitary hormone, prolactin (PRL), causes pigment dispersion in fish erythrophores and xanthophores. In the present study, therefore, cloning of PRL receptors in these chromatophores was performed and the receptors were identified as PRLR1 type. It was also suggested that the pigment dispersion by PRL is revealed through a novel signaling pathway, PRLR-Jak2-Grb2-Ras-adenylate cyclase (AC)-PKA pathway.
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会议论文
ゼブラフィッシュ黄色素胞におけるRasを介する新規プロラクチンシグナル伝達機構
斑马鱼黄色细胞中 Ras 介导的催乳素信号传导机制
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[矢野雄大, 西口慶一, 大島範子]
通讯作者:
大島範子
魚類黄色素胞におけるプロラクチン(PRL)のシグナル伝達とPRL受容体の発現
鱼类黄色细胞中催乳素 (PRL) 信号转导和 PRL 受体表达
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[矢野雄大, 西口慶一, 吉岡享, 大島範子]
通讯作者:
大島範子
A novel prolactin(PRL)signaling pathway in zebrafish xanthophores via Ras-adenylate cyclase(AC)-protein kinase A(PKA)
斑马鱼黄色细胞中通过Ras-腺苷酸环化酶(AC)-蛋白激酶A(PKA)的新型催乳素(PRL)信号通路
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[矢野雄大, 西口慶一, 吉岡享, 大島範子]
通讯作者:
大島範子
Therapeutic development for functional improvement of transplanted ovaries using regenerative medicine
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批准号:15K20131
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.33万
-
财政年份:2015
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负责人:OSHIMA Noriko
-
依托单位:
Analyses of visual pigments and G proteins coupled with them in light-sensitive chromatophores of teleost fishes
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批准号:17570068
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.03万
-
财政年份:2005
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负责人:OSHIMA Noriko
-
依托单位:
Analyses of the regulatory mechanisms of motile activities by factors other than neurotransmitters and hormones in teleost fish chromatophores
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批准号:14540637
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.79万
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财政年份:2002
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负责人:OSHIMA Noriko
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依托单位:
Analyses of direct action of light on fish chromatophores
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批准号:11640687
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.73万
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财政年份:1999
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负责人:OSHIMA Noriko
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依托单位:
Direct effect of prolactin on fish chromatophores and possible role of the hormone in change in body color
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批准号:07640915
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.47万
-
财政年份:1995
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负责人:OSHIMA Noriko
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依托单位:
MECHANISM OF MCH ACTION ON CHROMATOPHORES OF TELEOST FISH
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批准号:04640674
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1992
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负责人:OSHIMA Noriko
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依托单位:
Study of Signal Transduction and the Mechanism of Revelation of Motility in Fish Chromatophores
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批准号:63540590
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.58万
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财政年份:1988
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负责人:OSHIMA Noriko
-
依托单位: