Molecular design and enzyme inhibition mode using software supported by computer for antitumor active flavin derivatives

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The present study is the research for the purpose of the development of new antineoplastic drugs, which obstruct the tyrosine kinase of the enzyme concerned with the cell proliferation function adjustment and inhibit the tumor cell multiplication. We built the virtual screening system depended on the antitumor activities and docking data into the enzyme of deazaflavin analogs. The high, new and efficient search system, which can synthesize and evaluate the significant compounds designed as antitumor active compounds based on the virtual screening system, was constructed in this study.