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Mucin gene expression mechanism related to a new classification of pancreatobiliary neoplasms

Mucin gene expression mechanism related to a new classification of pancreatobiliary neoplasms
胰胆肿瘤新分类相关的粘蛋白基因表达机制
批准号:
20590345
负责人:
YONEZAWA Suguru
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The combination of MUC1, MUC2, MUC4 and MUC5AC expression is useful for early detection and evaluation of the potential for malignancy of pancreatobiliary neoplasms. Regarding the mechanism of mucin expression, we have recently reported that expression of the mucin genes is regulated epigenetically in cancer cell lines. A future translational research into mucin gene expression mechanisms, including epigenetics, may provide new tools for early and accurate detection of human pancreatobiliary neoplasms.
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DOI: 10.1158/0008-5472.can-07-6844
发表时间: 2008-04-15
期刊: CANCER RESEARCH
影响因子: 11.2
作者: [Yamada, Norishige, Nishida, Yukari, Yonezawa, Suguru]
通讯作者: Yonezawa, Suguru
Expression profiles of MUC1, MUC2, MUC4 and MUC5AC mucins in human neoplasms and their relationship with biological behavior, along with the epigenetic mechanism of mucin gene expression
人类肿瘤中MUC1、MUC2、MUC4和MUC5AC粘蛋白的表达谱及其与生物学行为的关系,以及粘蛋白基因表达的表观遗传机制
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Yonezawa, S.]
通讯作者: S.
DOI: 10.1007/s00534-009-0176-5
发表时间: 2010-05-01
期刊: JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
影响因子: 3
作者: [Higashi, Michiyo, Goto, Masamichi, Yonezawa, Suguru]
通讯作者: Yonezawa, Suguru
ムチンからみた腫瘍進展プロセス
从粘蛋白看肿瘤进展过程
DOI: --
发表时间: 2009
期刊: 肝胆膵 58
影响因子: --
作者: [米澤傑, 他]
通讯作者:
48
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