Development of early diagnosis of malignant mesothelioma : Comprehensive analysis of secretory and membrane proteins
Development of early diagnosis of malignant mesothelioma : Comprehensive analysis of secretory and membrane proteins
批准号:
20590377
负责人:
TSUJIMURA Tohru
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
We made monoclonal antibodies by using a malignant mesothelioma cell line as an immunogen, and obtained a clone of monoclonal antibody which reacts with a surface molecule of malignant mesothelioma, but not that of pulmonary adenocarcinoma. This clone showed strong immunoreactivity for malignant mesothelioma. In addition, we identified a cell adhesion molecule, which was expressed in malignant mesothelioma cells, but not reactive mesothelial cells, in pleural effusion. The clone of monoclonal antibody and the cell adhesion molecule may be useful for early diagnosis of malignant mesothelioma.
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DOI:
--
发表时间:
2010
期刊:
Lung Cancer. 67
影响因子:
--
作者:
[Torii I, Sato A, Tsujimura T, et al]
通讯作者:
et al
Circulating tumor cells (CTCs) and endothelial cells (CECs) in the diagnosis of malignant pleural mesothelioma (MPM) : a single institutional prospective stud
循环肿瘤细胞(CTC)和内皮细胞(CEC)在恶性胸膜间皮瘤(MPM)诊断中的应用:一项机构前瞻性研究
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Yoneda K, Tsujimura T, Nakano T et al]
通讯作者:
Nakano T et al
DOI:
10.1038/ni.1622
发表时间:
2008-07-01
期刊:
NATURE IMMUNOLOGY
影响因子:
30.5
作者:
[Uematsu, Satoshi, Fujimoto, Kosuke, Akira, Shizuo]
通讯作者:
Akira, Shizuo
DOI:
10.1038/ni.1885
发表时间:
2010-07
期刊:
Nature immunology
影响因子:
30.5
作者:
[]
通讯作者:
Diagnosis of malignant pleural mesothelioma in effusion cytology -Discrimination between mesothelioma and reactive mesothelium-
恶性胸膜间皮瘤的积液细胞学诊断-间皮瘤与反应性间皮瘤的鉴别-
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Okabe M, Tsujimura T, Miyajima A, et al, 辻村亨, Tsujimura T]
通讯作者:
Tsujimura T
共 28 条
Analysis of mechanisms by which malignant pleural mesothelioma grows and invades: application to pathological diagnosis and development of a new therapy
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批准号:23590438
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2011
-
负责人:TSUJIMURA Tohru
-
依托单位:
Study on the differentiation of oval cells for the development of liver-targeted regenerative medicine
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批准号:17590363
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.3万
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财政年份:2005
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负责人:TSUJIMURA Tohru
-
依托单位:
Regenerative medicine for liver diseases : Analysis of the development and differentiation of hepatic oval cells
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批准号:15590356
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2003
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负责人:TSUJIMURA Tohru
-
依托单位:
Analysis of liver regeneration : A study using c-kit mutants
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批准号:13670232
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
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财政年份:2001
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负责人:TSUJIMURA Tohru
-
依托单位:
Role of the signal transduction by c-kit receptor tyrosine kinase in the breast
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批准号:11670230
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
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财政年份:1999
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负责人:TSUJIMURA Tohru
-
依托单位:
Mechanism of carcinogenesis by the mutations of c-kit gene
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批准号:09670225
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
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财政年份:1997
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负责人:TSUJIMURA Tohru
-
依托单位:
Neoplastic transformation of mast cells through activating mutations of c-kit receptor
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批准号:07670245
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
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财政年份:1995
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负责人:TSUJIMURA Tohru
-
依托单位:
海外基金