TLR gene expression in e ndotoxin-induced lung injury
TLR gene expression in e ndotoxin-induced lung injury
批准号:
20590932
负责人:
IWASAKI Yoshinobu
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
In the experimental model of endotoxin-induced acute lung injury using rats, TLR4 gene and protein expression were found followed by apoptosis of alveolar epithelia. Soluble CD14 accelerated apoptosis of alveolar epithelia by activating TLR4. Inactivation of soluble CD14 reduced alveolar epithelial damage.
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DOI:
10.1016/j.bbrc.2009.01.122
发表时间:
2009-03
期刊:
Biochemical and biophysical research communications
影响因子:
3.1
作者:
[Takahiro Yamada;Yoshizumi Takemura;N. Niisato;E. Mitsuyama;Y. Iwasaki;Y. Marunaka]
通讯作者:
Takahiro Yamada;Yoshizumi Takemura;N. Niisato;E. Mitsuyama;Y. Iwasaki;Y. Marunaka
Chloride ions control the G1/S cell-cycle checkpoint by regulating the expression of p21 through a p53-independent pathway
氯离子通过 p53 独立途径调节 p21 的表达来控制 G1/S 细胞周期检查点
DOI:
--
发表时间:
2008
期刊:
human gastric cancer cells 66
影响因子:
--
作者:
[MIYAZAKI HIROAKI, SHIOZAKI ATSUSHI, NIISATA NAOMI, OHSAWA RUMI, ITOI H, UEDA Y, OTSUJI EIGO, YAMAGISHI HISAKAZU, IWASAKI YOSHINOBU, NAKANO T, NAKAHARI TAKASHI, MARUNAKA YOSHINORI]
通讯作者:
MARUNAKA YOSHINORI
Effect of inducible nitric oxide synthase on apoptosis in Candida-induced acute lung iniury.
诱导型一氧化氮合酶对念珠菌引起的急性肺损伤细胞凋亡的影响。
DOI:
--
发表时间:
2008
期刊:
Biomedical Research 29・5
影响因子:
--
作者:
[MIYAZAKI HIROAKI, SHIOZAKI ATSUSHI, NIISATA NAOMI, OHSAWA RUMI, ITOI H, UEDA Y, OTSUJI EIGO, YAMAGISHI HISAKAZU, IWASAKI YOSHINOBU, NAKANO T, NAKAHARI TAKASHI, MARUNAKA YOSHINORI, HOSOGI SHIGEKUNI]
通讯作者:
HOSOGI SHIGEKUNI
Intracellular Chloride Regulates Cell Proliferation Through the Activation of Stress-Activated Protein Kinases
细胞内氯化物通过激活应激激活蛋白激酶来调节细胞增殖
DOI:
--
发表时间:
2010
期刊:
MKN28 Human Gastric Cancer Cells Journal of Cellular Physiology 223
影响因子:
--
作者:
[OHSAWA RUMI, MIYAZAKI HIROAKI, NIISATO NAOMI, SHIOZAKI ATSUSHI, IWASAKI YOSHINOBU, OTSUJI EIGO, MARUNAKA YOSHINORI]
通讯作者:
MARUNAKA YOSHINORI
Action of N-acylated ambroxol derivatives on secretion of chloride ions
N-酰化氨溴索衍生物对氯离子分泌的作用
DOI:
--
发表时间:
2009
期刊:
hyuman airway epithelia 380
影响因子:
--
作者:
[YAMADA TAKAO, TAKEMURA YOSHIZUMI, NIISATO NAOMI, MITSUYAMA E, IWASAKI YOSHINOBU]
通讯作者:
IWASAKI YOSHINOBU
共 12 条
Translational Research for Clinical Application of Autologous Bone Marrow Stromal Cell Transplantation for CNS disorders
-
批准号:19390371
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.73万
-
财政年份:2007
-
负责人:IWASAKI Yoshinobu
-
依托单位:
Molecular regulation of ENaC in the process of recovery in permeability lung edema
-
批准号:18590861
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.43万
-
财政年份:2006
-
负责人:IWASAKI Yoshinobu
-
依托单位:
A basic study of gene and anti-angiogenic therapy for malignant brain tumor using bone marrow stromal cell and its potential of cell-fusion
-
批准号:16390401
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$7.23万
-
财政年份:2004
-
负责人:IWASAKI Yoshinobu
-
依托单位:
RESEARCH FOR BONE MARROW STROMAL CELLS (BMSC) TRANSPLANTATION THERAPY FOR INJURED CENTRAL NERVOUS SYSTEM USING BIOMATERIALS AND GENE ANALYSIS
-
批准号:15390426
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$8.06万
-
财政年份:2003
-
负责人:IWASAKI Yoshinobu
-
依托单位:
Molecular Pathological Analysis of the Differences in Biological Malignancy between S;inal and Intracranial Ependymomas
-
批准号:12671338
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.18万
-
财政年份:2000
-
负责人:IWASAKI Yoshinobu
-
依托单位:
of early drug administration on experimental spinal cord injury
-
批准号:03670668
-
项目类别:Grant-in-Aid for General Scientific Research (C)
-
资助金额:$1.28万
-
财政年份:1991
-
负责人:IWASAKI Yoshinobu
-
依托单位: