Investigation of the function of mitochondria in the oocytes during oocyte maturation in pigs.

猪卵母细胞成熟过程中卵母细胞线粒体功能的研究。

• 批准号: 20780198
• 负责人: YOKOO Masaki
• 金额: $ 2.75万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20780198/
• 关键词: 繁殖; ミトコンドリア機能; ブタ; 卵子; ミトコンドリア; 呼吸; 卵成熟

I investigated that the oxygen consumption of single porcine COCs and oocytes and the function of mitochondria in the oocytes during oocyte maturation. From this study, it is demonstrated that the oocytes with high oxygen consumption and ATP levels showed higher competence of oocyte maturation. Furthermore, these findings suggest that mitochondrial reorganization may be partly related to the oxygen consumption and consequently the quality of porcine oocytes.

我研究了单个猪COC和卵母细胞的耗氧量以及卵母细胞成熟过程中卵母细胞线粒体的功能。这项研究表明，耗氧量和 ATP 水平较高的卵母细胞表现出较高的卵母细胞成熟能力。此外，这些发现表明线粒体重组可能部分与耗氧量以及猪卵母细胞的质量有关。

项目成果

Morphological evaluation and measurement of the respiration activity of cumulus-oocyte complexes to assess oocyte quality.

对卵丘-卵母细胞复合物的呼吸活动进行形态学评估和测量，以评估卵母细胞质量。

• 发表时间: 2010
• 期刊: Journal of Mammalian Ova Research 26
• 作者: Haruo Murakawa;Nobuya Aono;TakayukiTanaka;Hiroyuki Kikuchi;Hidemune Yoshida;Hiroaki Yoshida;Masaki Yokoo;Hiroyuki Abe
• 通讯作者: Hiroyuki Abe

Influence of hyaluronan accumulation during cumulus expansion on porcine oocyte maturation in vitro

卵丘扩张过程中透明质酸积累对猪卵母细胞体外成熟的影响

• 发表时间: 2008
• 期刊: Zygote 16
• 作者: Kanada;K.;N. Asanuma;T. Hino;Yokoo et.al.
• 通讯作者: Yokoo et.al.

Embryo development after vitrification-thawing can be predicted by assessment of oxygen consumption.

玻璃化解冻后的胚胎发育可以通过评估耗氧量来预测。

• 发表时间: 2009
• 作者: Tanaka;et al.
• 通讯作者: et al.

Genomic Screening for Genes Silenced by DNA Methylation Revealed an Association between RASD1 Inactivation and Dexamethasone Resistance in Multiple Myeloma

• DOI: 10.1158/1078-0432.ccr-08-3336
• 发表时间: 2009-07-01
• 期刊: CLINICAL CANCER RESEARCH
• 影响因子: 11.5
• 作者: Nojima, Masanori;Maruyama, Reo;Shinomura, Yasuhisa
• 通讯作者: Shinomura, Yasuhisa

カラーアトラス 不妊診療のための卵子学

用于不孕症治疗的 Color Atlas Oovology

• 发表时间: 2010
• 作者: Yumi Hoshino;Yusuke Sato;Chizuka Sakai;Eimei Sato;星野由美;Yumi HOSHINO;星野由美(鈴木秋悦編);鈴木秋悦編
• 通讯作者: 鈴木秋悦編