Pathological study and transplantation of Bone marrow stromal cell in a model of amyotrophic lateral sclerosis

用常规染色和免疫组织化学方法对转基因小鼠腹角组织进行组织学检查。虽然结果是神经细胞在重度Will后开始脱落，但细胞器中的老化变性和细胞中的包涵体已经从早期出现。从临床和病理组织化学角度考虑，骨髓基质细胞移植对小鼠前路骨髓细胞间质量的影响。但结果表明，PORT组在延年益寿的作用下，组织学上还保留了脊髓腹角细胞，但作为临床疗效还不够。

Histological examination of the transgenic mice tissue at ventral horn using General stain and immunohistochemisity. Although the result is a nerve cell shedding onset after severe would mutant SOD1 are each in nerve cells, aging degenerative in organelle and inclusion bodies in cells had emerged from early. Therapeutic effect of Bone marrow stromal cell transplantation for anterior mice in quality between cell bone marrow, after consideration of clinical and pathological tissue chemically. However, as a result, port group in the life-prolonging effects, and histologically also remained a spinal cord ventral horn cells, but as a clinical effect was not enough.