Pathological study and transplantation of Bone marrow stromal cell in a model of amyotrophic lateral sclerosis

采用常规染色和免疫组织化学法对转基因小鼠腹角组织进行组织学检查。虽然结果是神经细胞脱落发作后严重会突变SOD1是每个神经细胞，老化退行性细胞器和包涵体在细胞中已经出现从早期。从临床和病理组织化学方面考虑，骨髓基质细胞移植对前代小鼠细胞间质骨髓的治疗作用。但结果是，端口组在延长寿命方面有效果，而且组织学上还保留了脊髓前角细胞，但作为临床效果还不够。

Histological examination of the transgenic mice tissue at ventral horn using General stain and immunohistochemisity. Although the result is a nerve cell shedding onset after severe would mutant SOD1 are each in nerve cells, aging degenerative in organelle and inclusion bodies in cells had emerged from early. Therapeutic effect of Bone marrow stromal cell transplantation for anterior mice in quality between cell bone marrow, after consideration of clinical and pathological tissue chemically. However, as a result, port group in the life-prolonging effects, and histologically also remained a spinal cord ventral horn cells, but as a clinical effect was not enough.