Novel hybrid bone filling material of self-assembling peptide scaffold and artificial framework

骨填充材料应具有足够的承重强度和足够的骨导电性。但这些属性是不相容的。在这项研究中，我们使用了自组装肽PuraMatrix和聚醚醚酮笼的杂化材料。PuraMatrix具有良好的骨导电性，聚醚酮笼具有足够的强度作为骨锉材料。结果表明，这些复合材料可用于大鼠股骨骨缺损的修复。

Bone filling materials should have enough strength for weight bearing and adequate osteoconductive property. But these properties are incompatible. In this study, we used hybrid materials of Self-assembling Peptide PuraMatrix and Polyetheretherketone Cage. PuraMatrix has good osteoconductive property and Polyetheretherketone Cage has enough strength for bone filing material. We showed that these hybrid materials were useful for repairing the bone defects in Rat's femurs.