The development of bone augmentation using the calcium carbonate of scallop shell and gelatin composite

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0.03mol, 0.05mol and 0.1mol calcium carbonate of scallop shell (CCSS) were contained in gelatin composite. 1%glutaraldhyde and 0.1mol CCSS contained composite was better than others. I conclude that the composite of 0.1mol contained CCSS was useful for biomaterials. It experimented on the animal for the confirmation of bone formation. The composites with dropping rhPDGF-BB were transplanted in subcutaneous back, bone formation was not observed. However tissue invading inside the composite was observed. From this result, rhPDGF-BB was useful for early tissue regeneration. The composite with cell formed a new bone.