Pathophysiology of Parkison disease : a review of cortico-basal ganglia loop model
Pathophysiology of Parkison disease : a review of cortico-basal ganglia loop model
批准号:
20591023
负责人:
SAWAMOTO Nobukatsu
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
点击翻译按钮获取中文摘要
英文摘要
In basal ganglia disorders, it is essential to clarify 'network dysfunction' in order to understand pathophysiological mechanisms from neuronal cell degeneration to clinical symptoms. Since the basal ganglia have no direct motor output, the network dysfunction should results in disordered outputs from the motor cortex reflecting the clinical symptoms. The present studies suggest that compensatory function of the cerebellum as well as disrupted function of cortico-basal ganglia loop should be considered in pathophydiological mechanisms of Parkinson disease.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
脳機能画像を用いた早期診断
使用功能性脑成像进行早期诊断
DOI:
--
发表时间:
2010
期刊:
最新医学 65
影响因子:
--
作者:
[Ueda K, Fujiwara H, Miyata J, Hirao K, Saze T, Kawada R, Fujimoto S, Tanaka Y, Sawamoto N, Fukuyama H, Murai T., 澤本伸克]
通讯作者:
澤本伸克
Suseeptibility-Weighted Imaging at 3 Tesla Delineates the Optic Radiation.
3 特斯拉磁化率加权成像描绘了光辐射。
DOI:
--
发表时间:
2009
期刊:
Invest Radiol. (in press)
影响因子:
--
作者:
[Mori N, Miki Y, Kasahara S, Maeda C, Kanagaki M, Urayama SI, Sawamoto N, Fukuyama H, Togashi K]
通讯作者:
Togashi K
The role of the uncinate fasciculus in memory and emotional recognition amnestic mild cognitive impairment
钩束在记忆和情绪识别遗忘性轻度认知障碍中的作用
DOI:
--
发表时间:
2008
期刊:
Dement Geriatr Cogn Disord 26
影响因子:
--
作者:
[Fujie S, Namiki C, Nishi H, Yamada M, Miyata J, Sakata D, Sawamoto N, Fukuyama H, Hayashi T, Murai T]
通讯作者:
Murai T
Pathophyisiology of Parkinson disease : neuroimaging approaches.
帕金森病的病理生理学:神经影像学方法。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[小栗卓也, 澤本伸克, 椨勇人, 浦山慎一, 松橋眞生, 小鹿幸生, 福山秀直, 澤本伸克, 澤本伸克, 澤本伸克, 澤本伸克, 澤本伸克]
通讯作者:
澤本伸克
Estimation of vascular contribution to DfMRI (Diffusion weighted fMRI) signal.
估计血管对 DfMRI(扩散加权 fMRI)信号的贡献。
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Urayama S, Aso K, Aso T, Kohno S, Sawamoto N, Fukuya H, LeBihan D]
通讯作者:
LeBihan D
共 69 条
Neuronal network connectivity breakdown in basal ganglia and cerebellar disorders
-
批准号:23591274
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.33万
-
财政年份:2011
-
负责人:SAWAMOTO Nobukatsu
-
依托单位:
海外基金