Probabilistic approach for the diagnosis and antimicrobial treatment for the lower respiratory tract infections caused by methicillin-resistant Staphylococcus aureus.

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Using a quantitative Baysian analysis as a clinical epidemiological approach, we developed a diagnostic strategy for lower respiratory tract infection (LRTI) caused by MRSA. These probabilistic diagnoses were closely corroborated with clinical diagnosis by infection control team. The diagnostic probabilities of MRSA-LRTI were reproducible, and reliable, hence it can be applied to the daily clinical practice of infection control and prevention in general medical centers.