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Screening of excreted proteins of Aspergillus fumigates for clinical application.

Screening of excreted proteins of Aspergillus fumigates for clinical application.
熏曲霉分泌蛋白的筛选及其临床应用
批准号:
20591212
负责人:
MIYAZAKI Yoshitsugu
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
We found some novel fungal proteins which natively exist on cell surface or are excreted out through cell membrane. Candidate proteins were chosen depending on levels of transcription for further experiments of gene cloning and of producing antibody, then confirmed that some proteins could be detected in culture medium. That showed those candidate, or at least a part of those, are excreted out to medium from fungal cell. We developed a preliminary diagnostic kit as an application of the study.
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会议论文
Serum or bile affects the in vitro azole susceptibilities of Candida spp.
血清或胆汁影响念珠菌属的体外唑类敏感性。
DOI: --
发表时间: 2009
期刊: Jpn J Infect Dis. 62(4)
影响因子: --
作者: [Nagi M, Tanabe K, Takano Y, Kikuchi K, Miyazaki Y, Niimi M]
通讯作者: Niimi M
真菌症の診断の現況と望まれる新しい診断法
真菌病诊断现状及所需的新诊断方法
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [森下慶子、(竹内啓晃, 他), 宮崎義継]
通讯作者: 宮崎義継
Micafungin alters the expression of genes related to cell wall integrity in Candida albicans biofilms.
米卡芬净改变白色念珠菌生物膜中与细胞壁完整性相关的基因的表达。
DOI: --
发表时间: 2010
期刊: Jpn J Infect Dis. 63(5)
影响因子: --
作者: [Kaneko Y, Ohno H, Kohno S, Miyazaki Y]
通讯作者: Miyazaki Y
DOI: 10.2169/internalmedicine.49.2759
发表时间: 2010-01-01
期刊: INTERNAL MEDICINE
影响因子: 1.2
作者: [Ohno, Hideaki, Ogata, Yoshiko, Miyazaki, Yoshitsugu]
通讯作者: Miyazaki, Yoshitsugu
19
    The analysis of the disease-causing gene of the tubercle bacillus and fundamental examination of tuberculosis attack control of the candidate new vaccine strain
    • 批准号:
      17590794
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.22万
    • 财政年份:
      2005
    • 负责人:
      MIYAZAKI Yoshitsugu
    • 依托单位:
    Research for antifungal mechanisms and therapeutics in refractory deep mycoses
    • 批准号:
      13670462
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.66万
    • 财政年份:
      2001
    • 负责人:
      MIYAZAKI Yoshitsugu
    • 依托单位:
    海外基金