Evaluation of new clinical biomarkers of carbon isotope using high field MR equipment.

本项目利用高场磁共振设备对碳同位素临床新标志物进行了评价。本研究利用600MHz核磁共振仪器，以超偏光器为基础，研究了一些碳化合物在癌细胞上的代谢。制作了一种用于临床磁共振设备的新型1H-13C表面线圈，并对其进行了评价，为临床研究做准备。成功地分析了碳同位素的性质，并利用临床磁共振设备进行了碳同位素的测量。

In this project, new clinical biomarkers of carbon isotope using high field MR equipment had been evaluated. We evaluated metabolism of some carbon compounds on cancer cell using 600MHz NMR equipment with hyperpolarizer as basic study. A new 1H-13C surface coil for clinical MR equipment had been made and evaluated as for preparation of clinical study. Analyses of the properties of carbon isotope and the measurement of carbon isotope using clinical MR equipment had been succeeded.