Epidermal cooling for spinal cord protection against ischemia

表皮冷却可保护脊髓免受缺血

• 批准号: 20591641
• 负责人: TABAYASHI Koichi
• 金额: $ 3万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20591641/
• 关键词: 心臓大血管外科学; 神経保護; 脊髄保護; 局所冷却

Epidermal cooling may bring protective effect against ischemia on deep tissue such as spinal cord which can be suffered from ischemia during clinical thoracoabdominal aortic repair. Computed simulation model on deep tissue temperature change by epidermal cooling has been established by the experimental evaluations both on animal and human models. However, clinical application was not accepted because the preliminary study showed that mild frostbite occurred on normal tissue after epidermal cooling.

在临床胸腹主动脉修补术中，表皮冷却可能对脊髓等深部组织产生缺血保护作用。通过对动物和人体模型的实验评估，建立了表皮冷却引起深部组织温度变化的计算机仿真模型。但临床应用未被接受，因为初步研究显示，表皮冷却后，正常组织发生轻度冻伤。

项目成果

Development and estimation of a novel cryoprobe utilizing the Peltier effect for precise and safe cryosurgery

开发和评估利用珀耳帖效应的新型冷冻探针，以实现精确、安全的冷冻手术

• 发表时间: 2009
• 期刊: Cryobiology 59
• 作者: Takeda;H.;Maruyama;S.;Okajima;J.;Aiba;S.;Komiya;A.
• 通讯作者: A.

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The effect of using some common white pigments on thermal and aesthetic performances of pigmented coatings.

使用一些常见白色颜料对着色涂料的热性能和美观性能的影响。

• 发表时间: 2009
• 期刊: J thermal Sci Tech 1
• 作者: Baneshi M;Maruyama S;Nakai H;Komiya A.
• 通讯作者: Komiya A.

Evaluation methods for radiative heat transfer in polydisperse water droplets.

多分散水滴辐射传热的评价方法。

• 发表时间: 2008
• 期刊: J Quant Spect Radia Transfer. 109(1)
• 作者: Maruyama S;Nakai H;Komiya A.
• 通讯作者: Komiya A.

Efficacy of perfusion cooling of the epidural space and cerebral fluid drainage during repair of extent I and II thoracoabdominal aneuyrysm

硬膜外腔灌注冷却和脑液引流在Ⅰ、Ⅱ级胸腹动脉瘤修复中的疗效

• 发表时间: 2008
• 期刊: J Cardiovasc Surg (Torino) Dec ; 49(6)
• 作者: Maruyama S;Nakai H;Komiya A.;Tabayashi K
• 通讯作者: Tabayashi K