Clinical application of artificial intervertebral disc and development of novel hybrid type regenerative disc

人工椎间盘的临床应用及新型混合型再生椎间盘的研制

• 批准号: 20591734
• 负责人: KOTANI Yoshihisa
• 金额: $ 2.91万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20591734/
• 关键词: 脊椎脊髄病学; 生体材料; 椎間板; 再生医学; 人工椎間板; 臨床治験; 間葉系幹細胞; 培養髄核細胞; 三次元立体織物

For clinical application of artificial disc, we received the starting approval from PMDA and continued the negotiation with US company. For the regenerative disc research, we selected mesenchymal stem cell or cultured nucleus cell for regenerative cells. The bioabsorbable microfiber was fabricated into the three-dimensional configuration for three-dimensional scaffold.

对于人工椎间盘的临床应用，我们获得了PMDA的启动批准，并继续与美国公司进行谈判。在再生椎间盘的研究中，我们选择间充质干细胞或培养的核细胞作为再生细胞。将生物可吸收超细纤维制成三维结构，用于三维支架。

项目成果

Spinal cord compression by ligamentum flavum hematoma in the thoracic spine

胸椎黄韧带血肿压迫脊髓

• 发表时间: 2009
• 期刊: Spine 34
• 作者: Kim K;Emoto N;Mishina M;Okada S;Isu T;Yoshida D;Kobayashi S;Teramoto A.;放生憲博;Sudo H;放生憲博;放生憲博;Sudo H
• 通讯作者: Sudo H

A late neurological complication followig posterior correction surgery of severe cervical kyphosis.

严重颈椎后凸后路矫正手术后的晚期神经系统并发症。

• 发表时间: 2010
• 期刊: Eur Spine J Epub ahead of print
• 作者: Hojo Y;Ito M;Abumi K;Kotani Y;Sudo H;Takahata M;Minami A
• 通讯作者: Minami A

Minimum two-year outcome of cervical laminoplasty with deep extensor muscle preserving approach : Impact on cervical spine function and quality of life.

采用深伸肌保留方法的颈椎椎板成形术的至少两年结果：对颈椎功能和生活质量的影响。

• 发表时间: 2009
• 期刊: Eur Spine J 18
• 作者: Kotani Y;Abumi K;Ito M;Sudo H;Takahata M;Ohshima S;Hojo Y;Minami A
• 通讯作者: Minami A

2010 American Academy of Orthopaedic Surgeons(Cervical pedicle screw fixation. Chapter 21)

2010年美国骨科医师学会（颈椎椎弓根螺钉固定。第21章）

• 发表时间: 2010
• 作者: Abumi K;Ito M;Kotani Y
• 通讯作者: Kotani Y

Neurological recovery after surgical treatment of giant cervical pseudomeningoceles extending to lumbar spine associated with previous brachial plexus injury

• DOI: 10.1007/s00586-010-1387-9
• 发表时间: 2010-07-01
• 期刊: EUROPEAN SPINE JOURNAL
• 影响因子: 2.8
• 作者: Kotani, Yoshihisa;Abumi, Kuniyoshi;Minami, Akio
• 通讯作者: Minami, Akio