The new treatment strategy for the perinatal brain damage with the mesenchymal stem cell derived from fetal appendages
The new treatment strategy for the perinatal brain damage with the mesenchymal stem cell derived from fetal appendages
批准号:
20591914
负责人:
KANAGAWA Takeshi
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
The Perinatal brain damage due to the fetal distress or neonatal distress remains the most important problem although the perinatal care develops rapidly remarkably.The aims of this research are the decrease the perinatal damage. In this research, we discovered that C-Reactive protein makes the immature brain susceptible to Hypoxic ischemic insult, even if the insult causes little or no injury by itself. We also clarified that the preconditioning by the beta-lactam antibiosis protects the immature brain damage.
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Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in in vitro model of preeclamptic vascular endothelium : apossible therapeutic role of nicotinic acetylcholine receptor(nAChR)agoonists for preeclampsia.
尼古丁恢复子痫前期血管内皮体外模型中过量 sFlt1 和 sEng 引起的内皮功能障碍:烟碱乙酰胆碱受体 (nAChR) 激动剂对先兆子痫的可能治疗作用。
DOI:
--
发表时间:
2010
期刊:
Am J Obstet Gynecol
影响因子:
9.8
作者:
[Mimura K, Tomimatsu T]
通讯作者:
Tomimatsu T
Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus
妊娠小鼠子宫中肿瘤相关抗原RCAS1的时空表达
DOI:
--
发表时间:
2010
期刊:
Am J Reprod Immunol. 63
影响因子:
--
作者:
[Tskitishvili E, Nakamura H, Kinugasa-Taniguchi Y, Kanagawa T, Kimura T, Tomimatsu T, Shimoya K.]
通讯作者:
Shimoya K.
Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in in vitro model of preeclamptic vascular endothelialium
尼古丁可恢复先兆子痫体外血管内皮模型中过量 sFlt1 和 sEng 引起的内皮功能障碍
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[味村和哉, et al.]
通讯作者:
et al.
産科超音波の基礎-妊娠初期から中期までの超音波スクリーニング-
产科超声基础知识 - 从怀孕早期到中期的超声筛查 -
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[MH Hussein, Ghada A. Daoud, Hiroki Kakita, Shin Kato, Tatenubo Goto, Michi Kamei, Kenji Goto, Yasuhiko Ozaki, Tetsuya Ito, Sumio Fukuda, Ineko Kato, Satoshi Suzuki, Takashi Hashimoto, Hajime Togari, 金川武司]
通讯作者:
金川武司
Nicotine suppresses interleukin-6 production from vascular endothelial cells.
尼古丁抑制血管内皮细胞产生白细胞介素 6。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Tomimatsu T, Syarentuya N, Mimura K, Tskitishvili E, Kinugasa-Taniguchi Y, Kanagawa T, Kimura T.]
通讯作者:
Kimura T.
共 41 条
A trial of the establishment of the umbilical cord blood stem cell transplantation for the neonatal brain injury: a search for the effective transplantation -
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批准号:23592402
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:KANAGAWA Takeshi
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依托单位:
海外基金