Study on regulation of gene expression of a novel female reproductive organ-specific Type I interferon
Study on regulation of gene expression of a novel female reproductive organ-specific Type I interferon
批准号:
20591934
负责人:
MATSUMIYA Tomoh
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
IFN (interferon)-εhas recently found as a female reproductive-specific Type I IFN. From a point of view including sexually transmitted disease, it is important to understand local immune response in female-reproductive organs such as uterus and ovary ; however, it is incompletely understood. We elucidated a part of the mechanism of IFN-εgene expression. This result is expected to understand the local immune response in the female reproductive tissue.
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HuR regulates synergistic induction of CX3CL1 by TNF-alpha and IFN-gamma in vascular endothelial cells.
HuR 调节血管内皮细胞中 TNF-α 和 IFN-γ 对 CX3CL1 的协同诱导。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Matsumiya T, Imaizumi T, Yoshida H,Satoh K]
通讯作者:
Yoshida H,Satoh K
DOI:
10.4161/cc.9.1.10250
发表时间:
2010-01-01
期刊:
CELL CYCLE
影响因子:
4.3
作者:
[Ota, Ken, Matsumiya, Tomoh, Satoh, Kei]
通讯作者:
Satoh, Kei
Tumor-necrosis factor-alpha induces retinoic acid-inducible gene-I in rheumatoid fibroblast-like synoviocytes.
肿瘤坏死因子-α 在类风湿成纤维细胞样滑膜细胞中诱导视黄酸诱导基因-I。
DOI:
--
发表时间:
2009
期刊:
Immunol Lett. 122(1)
影响因子:
--
作者:
[Imaizumi T, Matsumiya T, Yoshida H, Naraoka T, Uesato R, Ishibashi Y, Ota K, Toh S, Fukuda S, Satoh K]
通讯作者:
Satoh K
Edaravone improves the expression of nerve growth factor in human astrocytes subjected to hypoxia/reoxygenation
依达拉奉改善缺氧/复氧的人星形胶质细胞中神经生长因子的表达
DOI:
10.1016/j.neures.2009.11.011
发表时间:
2010
期刊:
Neurosci Res
影响因子:
2.9
作者:
[Yoshida H, Metoki N, Ishikawa A, Imaizumi T, Matsumiya T, Tanji K, Ota K, Ohyama C, Satoh K]
通讯作者:
Satoh K
Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.
干扰素-α2b 诱导 HeLa 细胞中 p21cip1/waf1 降解和细胞增殖。
DOI:
--
发表时间:
2010
期刊:
Cell Cycle
影响因子:
4.3
作者:
[Ota K, et al.]
通讯作者:
et al.
共 16 条
Elucidation of interorganelle network in RLRs-mediated innate immunity
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批准号:23590560
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.33万
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财政年份:2011
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负责人:MATSUMIYA Tomoh
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依托单位: