Role of C/EBPβ, a transcription factor in neutrophils, in the pathogenesis of septic acute lung injury

中性粒细胞转录因子 C/EBPβ 在脓毒症急性肺损伤发病机制中的作用

• 批准号: 20592125
• 负责人: SHIME Nobuaki
• 金额: $ 2.91万
• 依托单位: Kyoto Prefectural University of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20592125/
• 关键词: 集中治療医学; 好中球; 急性肺損傷; 敗血症; 転写因子; C/EBPβ; C; EBPβ; 造血過程; フローサイトメーター

The purpose of this study is to obtain basic data for maintaining proper body weight by controlling obesity following childbirth. The levels of autonomic nerve activity and body composition were measured in pregnant and puerperal women by analyzing the power spectra of heat rate fluctuations. Results 1) Parasympathetic nerve activity decreased while sympathetic nerve activity increased in the third trimester as compared with the second trimester. 2) Increased body fat percentage, decreased muscle volume and increased autonomic nerve activity were confirmed following childbirth. The results of this study can be applied to the development of a proper weight management program for use after childbirth by monitoring BMI and body composition starting one year after childbirth.

这项研究的目的是获得通过控制产后肥胖来保持适当体重的基础数据。通过分析热率波动的功率谱，测量了孕妇和产后妇女的自主神经活动水平和身体成分。结果1)与中期相比，妊娠晚期副交感神经活动降低，交感神经活动增加。(2)产后体脂百分比增加，肌肉体积减少，自主神经活动增强。这项研究的结果可以应用于通过监测出生后一年开始的BMI和身体成分来制定适当的出生后体重管理计划。

项目成果

Performance of evidence-based preventive measures for ventilator-associated pneumonia in Japanese healthcare settings.

日本医疗机构中呼吸机相关肺炎循证预防措施的实施。

• 发表时间: 2010
• 作者: Shime N;Satake S;Hosokawa K;Hashimoto S
• 通讯作者: Hashimoto S

人工呼吸器関連肺炎のすべて

关于呼吸机相关性肺炎的一切

• 发表时间: 2010
• 作者: 小笠原理恵;菱川大介;進藤英雄;清水孝雄;林秀一郎;吉田康夫;遠山稿二郎;諏訪部章;志馬伸朗(編著)
• 通讯作者: 志馬伸朗(編著)

顆粒球造血過程をとらえるためのフローサイト新染色法を用いた敗血症病態の検討

使用新的流式细胞学染色方法来捕获粒细胞造血过程来检查脓毒症病理学

• 发表时间: 2009
• 作者: 佐竹早紀子、平位秀世、志馬伸朗;ら
• 通讯作者: ら

Prediction of Pediatric Endotracheal Tube Size by Ultrasonography

• DOI: 10.1097/aln.0b013e3181ef6757
• 发表时间: 2010-10-01
• 期刊: ANESTHESIOLOGY
• 影响因子: 8.8
• 作者: Shibasaki, Masayuki;Nakajima, Yasufumi;Sessler, Daniel I.
• 通讯作者: Sessler, Daniel I.

Use of bicistronic vectors in combination with flow cytometry to screen for effective small interfering RNA target sequences.

• DOI: 10.1016/j.bbrc.2010.02.033
• 发表时间: 2010-03-12
• 期刊: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
• 影响因子: 3.1
• 作者: Kamio, Naoka;Hirai, Hideyo;Ashihara, Eishi;Tenen, Daniel G.;Maekawa, Taira;Imanishi, Jiro
• 通讯作者: Imanishi, Jiro