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The difference of nature and functional role between tumor-nest versus tumor-stroma infiltrating lymphocytes in oral cancer.

The difference of nature and functional role between tumor-nest versus tumor-stroma infiltrating lymphocytes in oral cancer.
口腔癌中肿瘤巢与肿瘤基质浸润淋巴细胞之间的性质和功能作用的差异。
批准号:
20592325
负责人:
KATOU Fuminori
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
翻译
我们确定了肿瘤巢和肿瘤间质浸润淋巴细胞,并检查其功能作用和激活状态。在肿瘤巢中,抑制性CD8+ CTL丰富,但在肿瘤间质中,它们很少。相反,活化的CD8+ CTL和CD4+ T细胞向肿瘤间质浸润。
英文摘要
We identified the tumor-nest and tumor-stroma infiltrating lymphocytes, and examined their functional role and activation status. In the tumor nest inhibitory CD8+ CTLs were abundant, but in the tumor stroma they were scarce. On the contrary, activated CD8+ CTLs and CD4+ T cells plentifully infiltrated to the tumor stroma.
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DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
口腔扁平上皮癌に浸潤する制御性T細胞の密度は生命予後を規定する
浸润口腔鳞状细胞癌的调节性T细胞密度决定生命预后
DOI: --
发表时间: 2008
期刊:
影响因子: --
作者: [渡邉賀子, 加藤文度, 田中秀生, 増本一真, 大浦健宏, 内山佳之, 薗田直志, 長田哲次, 橋本賢二]
通讯作者: 橋本賢二
DOI: 10.1016/j.tripleo.2009.12.015
发表时间: 2010-05-01
期刊: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
影响因子: --
作者: [Watanabe, Yoshiko, Katou, Fuminori, Hashimoto, Kenji]
通讯作者: Hashimoto, Kenji
DOI: 10.4049/jimmunol.0904126
发表时间: 2010-12-01
期刊: JOURNAL OF IMMUNOLOGY
影响因子: 4.4
作者: [Nakayama, Takashi, Watanabe, Yoshiko, Yoshie, Osamu]
通讯作者: Yoshie, Osamu
The role of dendritic cells in oral cancer
  • 批准号:
    23592918
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $3.08万
  • 财政年份:
    2011
  • 负责人:
    KATOU Fuminori
  • 依托单位:
The role of chemokine system on the metastasis to the lymph node in oral cancer and its clinical application.
  • 批准号:
    17592071
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.22万
  • 财政年份:
    2005
  • 负责人:
    KATOU Fuminori
  • 依托单位:
Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in the encapsulation process against titanium implant
  • 批准号:
    10671860
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.15万
  • 财政年份:
    1998
  • 负责人:
    KATOU Fuminori
  • 依托单位:
Expression of TGF-beta in foreign body reaction and fibrosis agaist titanium implant.
  • 批准号:
    08672286
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $1.34万
  • 财政年份:
    1996
  • 负责人:
    KATOU Fuminori
  • 依托单位:
海外基金