Detailed estimation of local circuit structure based on spike time reliability of cortical neurons

基于皮层神经元尖峰时间可靠性的局部电路结构的详细估计

• 批准号: 20700304
• 负责人: TERAMAE Junnosuke
• 金额: $ 2.25万
• 依托单位: The Institute of Physical and Chemical Research
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20700304/
• 关键词: リミットサイクル; 確率過程; ノイズ; スパイク; 発火率; 対数正規分布; ネットワーク; 理論神経科学; 計算論的神経科学; 大脳皮質; 揺らぎ; 非線形振動子; 確率微分方程式; 情報表現; 同期; 位相; temoral coding

Isolated cortical neurons have known to respond to fluctuating inputs with high temporal precision about few milliseconds. The reliable responses of neurons, however, may be influenced local network structure in cortex. Here, we provided theories which clarify relationship between response reliability of neurons and potential factors including network structure, intrinsic properties of neurons, EPSP (excitatory-postsynaptic potentiation) distribution, and statistics of input signals. We have also reveals possible generation mechanism of fluctuating input to cortical neurons and computational role of them.

已知孤立的皮质神经元对波动输入的反应具有大约几毫秒的高时间精度。然而，神经元的可靠反应可能受皮层局部网络结构的影响。本文提出了神经元响应可靠性与网络结构、神经元内在特性、EPSP分布和输入信号统计等潜在因素之间关系的理论。我们还揭示了皮质神经元波动输入的可能产生机制及其计算作用。

项目成果

裾野の広いEPSP分布は大脳皮質のUP状態、低頻度非同期発火、精緻な発火時系列を一括して説明する

宽尾 EPSP 分布共同解释了大脑皮层的 UP 状态、低频异步放电以及复杂的放电时间序列。

• 发表时间: 2010
• 作者: 寺前順之介;深井朋樹
• 通讯作者: 深井朋樹

Noise-induced synchronization of coupled oscillators and precision of spike coding in the brain

噪声引起的耦合振荡器同步和大脑尖峰编码的精度

• 发表时间: 2008
• 作者: 寺前順之介;深井朋樹;Atsuhiko Yoshida;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae

Spike timing and possible roles of noise in cortical computation

尖峰时序和噪声在皮层计算中的可能作用

• 发表时间: 2010
• 作者: Jun-nosuke Teramae;Tomoki Fukai;Jun-nosuke Teramae;Jun-nosuke Teramae;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae

Long-tailed EPSP distribution accounts for low-rate asynchronous firings, the up-state, and precise firing sequences in cortical networks

长尾 EPSP 分布解释了皮质网络中的低速率异步放电、上状态和精确放电序列

• 发表时间: 2010
• 作者: Jun-nosuke Teramae;Tomoki Fukai;Jun-nosuke Teramae;寺前順之介;Jun-nosuke Teramae
• 通讯作者: Jun-nosuke Teramae

Stochastic phase reduction for a general class of noisy limit cycle oscillators.

• DOI: 10.1103/physrevlett.102.194102
• 发表时间: 2009-05
• 期刊: Physical review letters
• 影响因子: 8.6
• 作者: Jun-nosuke Teramae;H. Nakao;G. Bard Ermentrout