Development of high-speed time domain optical coherence tomography and imaging of blood vessels

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We developed a high-speed linear detection time-domain optical coherence tomography (OCT) technique that detected a reflective grating-generated spatial optical delay in the reference arm using a line scan camera during probe-beam scanning. The image processing that involve a reference intensity removal, high pass fingering 1 D Hilbert transform and log scaling were accelerated by the GPU (graphics processing unit) with many stream processors, which realized highly parallel processing. A display rate of 94 frames per second for processed images with 500 lateral A-scans was achieved using an InGaAs line scan camera (512 pixels) operated at 47,000 lines/s. Our OCT system was successfully used to image the human finger in vivo with 93-dB sensitivity.