Development of a method to control acoustic cavitation withdual-frequency ultrasound for therapeutic use

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Ultrasound treatment has attracted much attention as a treatment for cancer, and many researchers have investigated the method. One of the big topics of the investigation is to control of cavitation bubbles induced by therapeutic ultrasound. In this study, dual-frequency method was investigated to generate cavitation with lower intensity ultrasound and control the cavitation bubbles. The results showed that it is important to choose the frequency and the phase difference of the two-frequency ultrasound depending on the properties of the bubbles.