Analysis of muscle functions in exercise by producing exercise-reporter animals.

我们研究了转基因动物在运动和骨骼肌研究中的可用性，这些动物携带一个报告基因，编码由运动诱导启动子驱动的短半衰期报告蛋白。报告蛋白的表达水平不一定足以监测运动对个体肌肉活动的影响。然而，这些动物为设计运动报告基因以创建运动报告转基因动物提供了重要的见解。

We investigated the usability of transgenic animals, harboring a reporter gene encoding a short half-life reporter protein driven by the exercise-inducible promoter, on exercise and skeletal muscle study. The expression levels of reporter proteins were not necessarily enough to monitor the effect of exercise on individual muscle activity. However, these animals provide important insights in designing an exercise-reporter transgene to create an exercise-reporter transgenic animal.