Screening of food components for the prevention of alcoholic liver diseases and their application

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We studied the protection against ethanol-induced liver injury by various food components. The goal of this study is to propose a utilization of them into our dietary habits for the prevention of the disease. We examined the protective effect of various food components by using in vitro cell culture models for hepatitis and for liver cirrhosis and an in vivo animal model for liver disease, which were developed by us. Then we got the following results. We found that Ecklonia cava extract, extract from Tamatsukuri-kuromon Shirouri, sesame lignin and Mate tea extract have the protective effects for ethanol-induced liver injury on our in vitro and in vivo models and suggested that the ingestion of these components is useful for our healthy life.