Investigations of the mechanical properties of the spinal cord at high strain rates for computer simulation model of the spinal cord injury

研究脊髓损伤计算机模拟模型高应变率下脊髓的力学特性

• 批准号: 21560107
• 负责人: SAKURAMOTO Itsuo
• 金额: $ 2.08万
• 依托单位: Tokuyama College of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21560107/
• 关键词: 生体力学; 生体材料; 生物・生体工学; 医療・福祉

In the present study, we made the original high speed tensile equipment(Maximum crosshead speed 1, 000mm/s), and investigated the mechanical properties of the pia mater(postero-lateral sulcus, posterior median septum, dentate ligament) andspinal parenchyma(gray matter, white matter), which are the important parts to analyze the stress distribution within the spinal cord. The results exhibit the characteristic nonlinear and viscoelastic stress-strain response, in which the stiffness of the material increases with strain and strain rate. Furthermore, the gray matter is stiffer but fails at a lower mechanical strain than the white matter at high strain rates.

在本研究中，我们制作了原装高速拉伸装置（最大十字头速度为1000 mm/s），并对分析脊髓内应力分布的重要部位——脊髓硬膜（后外侧沟、后中隔、齿状韧带）和脊髓实质（灰质、白质）的力学特性进行了研究。结果表明，材料的刚度随应变和应变速率的增大而增大，具有典型的非线性粘弹性应力-应变响应特征。此外，在高应变率下，灰质比白质更硬，但在较低的机械应变下失效。