课题基金 / 基金详情

Cell and signal mechanisms that support tissue regeneration in fish

Cell and signal mechanisms that support tissue regeneration in fish
支持鱼类组织再生的细胞和信号机制
批准号:
21570004
负责人:
KAWAKAMI Atsushi
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

KAWAKAMI Atsushi的其他基金

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中文摘要
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英文摘要
To clarify the tissue homeostasis mechanism of multicellular organisms, we analyzed the regeneration processes of adult and larval zebrafish tissues and obtained the following results.1. The signaling pathway involving the Junb, Junbl and JNK has an essential role in regeneration.2. To reveal the origin and fate of regenerating cells, we generated transgenic lines for cell fate tracing and cell ablation.3. From the analysis of regeneration defective zebrafish mutant, we showed that a factor derived from the hematopoietic tissues is necessary for the survival of regenerating cells.
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会议论文
Epigenetic control mechanism of cardiomyocyte production in response to a stress during the medaka heart development
青鳉心脏发育过程中心肌细胞产生应激反应的表观遗传控制机制
DOI: --
发表时间: 2010
期刊: Developmental Biology
影响因子: 2.7
作者: [Taneda, Y., Konno, S., Makino, S., Fukuda, K., Imai, Y., Kudo, A. and Kawakami, A.]
通讯作者: A.
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Atsushi Kawakami, Natsumi Horita, Tomomi Kushida, Kazunori Ando, EmikoMurase, Nozomi Yoshianri, Masato Kinoshita, Genbu Abe, Koichi Kawakami, and Tohru Ishitani]
通讯作者: and Tohru Ishitani
Cell lineage analysis of fish fin blastema for their potential producing multiple cell types during regeneration
鱼鳍胚基的细胞谱系分析,了解其在再生过程中产生多种细胞类型的潜力
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Nozomi Yoshinari, Akira Kudo, ^○Atsushi Kawakami]
通讯作者: ^○Atsushi Kawakami
DOI: 10.1086/bblv221n1p62
发表时间: 2011-08
期刊: The Biological Bulletin
影响因子: --
作者: [Nozomi Yoshinari;A. Kawakami]
通讯作者: Nozomi Yoshinari;A. Kawakami
26
    Basic research for searching of new therapeutic targets of rheumatoid arthritis through investigation of novel action of CTLA-4-Ig
    • 批准号:
      15K09531
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2015
    • 负责人:
      KAWAKAMI Atsushi
    • 依托单位:
    Investigation of autoantigens in patients with rheumatoid arthritis through protemic analysis: exploration from diagnosis, pathogenesis to therapy
    • 批准号:
      23591439
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.24万
    • 财政年份:
      2011
    • 负责人:
      KAWAKAMI Atsushi
    • 依托单位:
    Can we explain the varying pathologic processes of rheumatoid arthritis by CaMKII delta abnormality?
    • 批准号:
      20591173
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.91万
    • 财政年份:
      2008
    • 负责人:
      KAWAKAMI Atsushi
    • 依托单位:
    Investigation for the possibility of CaMKII activity modulation for the therapeutic optical in rheumatoid arthritis
    • 批准号:
      18591116
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.49万
    • 财政年份:
      2006
    • 负责人:
      KAWAKAMI Atsushi
    • 依托单位: