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Analysis of regulations of septin modifications in cytokinesis

Analysis of regulations of septin modifications in cytokinesis
septin修饰在胞质分裂中的调控分析
批准号:
21570003
负责人:
KIKUCHI Yoshiko
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012

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中文摘要
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英文摘要
Budding yeast Cdc3 is a component of septin rings which localize at the neck region andis essential for cytokinesis. Cdc3 was transiently sumoylated by Siz1, a SUMO ligase onlyduring M-phase. Cdc3 was ubiquitinated in Rsp5-dependent way, but the PY-motif of Cdc3was not required for the ubiquitination. We examined the phenotypes of various mutantswhen Siz1-septin or SUMO-septin fusion proteins were over-expressed. Results suggestedthat the septin sumoylation induces the depolymerization of septin rings, and that thesumolylated Siz1 was ubiquitinated by Slx8/Slx5 ubiquitin ligase for its degradation.
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Solution structures and DNA binding properties of the N-terminal SAP domain of SUMO E3 ligase from Saccharomyces cerevisiae and Oryza sativa.
来自酿酒酵母和稻的 SUMO E3 连接酶 N 端 SAP 结构域的溶液结构和 DNA 结合特性。
DOI: --
发表时间: 2009
期刊: Proteins
影响因子: 2.9
作者: [Suzuki,R., et al.]
通讯作者: et al.
Regulations of Mih1-phosphatase in buddingyeast
Mih1-磷酸酶在芽殖酵母中的调控
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [松岡聡, 原弘志, 松本幸次, Kouitiro Yano and Yoshiko Kikuchi]
通讯作者: Kouitiro Yano and Yoshiko Kikuchi
Regulations of Mih1-phosphatase in budding yeast
Mih1-磷酸酶在芽殖酵母中的调控
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kikuchi, Y.]
通讯作者: Y.
Structural analysis of compounds withactions similar to local anesthetics andantipsychotic phenothiazines in yeast
酵母中具有类似局麻药和抗精神病药吩噻嗪类作用的化合物的结构分析
DOI: 10.1002/yea.1846
发表时间: 2011
期刊: Yeast
影响因子: 2.6
作者: [Yukifumi Uesono, Akio Toh-e, YoshikoKikuchi, Ichiro Terashima]
通讯作者: Ichiro Terashima
8
    Mechanism of the G2/M transition of the budding yeast cell cycle
    • 批准号:
      14390015
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $8.38万
    • 财政年份:
      2002
    • 负责人:
      KIKUCHI Yoshiko
    • 依托单位:
    Molecular and genetical analysis of inducing factors for the G2/M transition in yeast.
    • 批准号:
      08680736
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.54万
    • 财政年份:
      1996
    • 负责人:
      KIKUCHI Yoshiko
    • 依托单位:
    Expression and localization of the gene products necessary for cell proliferation
    • 批准号:
      04680254
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.28万
    • 财政年份:
      1992
    • 负责人:
      KIKUCHI Yoshiko
    • 依托单位:
    Analysis of the genes involved in the maintenance of mini-chromosomes in yeast.
    • 批准号:
      63580208
    • 项目类别:
      Grant-in-Aid for General Scientific Research (C)
    • 资助金额:
      $1.79万
    • 财政年份:
      1988
    • 负责人:
      KIKUCHI Yoshiko
    • 依托单位:
    海外基金