Studies on the protective effect of acetate on metabolic syndrome
Studies on the protective effect of acetate on metabolic syndrome
批准号:
21580150
负责人:
YAMASHITA Hiromi
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
Previously, we reported that oral administrated acetate contributed to suppression of lipogenesis in the liver, to the reduction of lipid accumulation in adipose tissue, and to the improvement of glucose tolerance of Otsuka Long-Evans Tokushima Fatty(OLETF) rats. Acetate has a potential for prevention of metabolic syndrome. In this study, we investigated the effect of acetate on skeletal muscle and adipose tissue. It was shown that acetate stimulated expressions of myoblobin and GLUT4 via activation of AMP-activated protein kinase(AMPK) and it enhanced fatty acid metabolism and glucose uptake in skeletal muscle.
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L6細胞における分化レベルによるAMPKおよびMEF2Aの細胞内局在変化とそれらに及ぼす酢酸の影響
AMPK 和 MEF2A 亚细胞定位的变化取决于 L6 细胞的分化水平以及乙酸对其的影响
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[田中あや, 丸田ひとみ, 我如古菜月, 木本眞順美, 辻英明, 高橋吉孝, 山下広美]
通讯作者:
山下広美
酢酸の代謝と酢酸が脂質代謝に及ぼす影響に関する研究
乙酸代谢及其对脂质代谢影响的研究
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[丸山祐佳, 土井絵梨子, 中田和江, 我如古菜月, 木本眞順美, 辻英明, 高橋吉孝, 山下広美, 山下広美]
通讯作者:
山下広美
黒米の色素成分シアニジン3-グルコシドの加熱分解産物の熱安定性と抗酸化能について
黑米色素成分花青素3-葡萄糖苷热分解产物的热稳定性和抗氧化能力
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Koizumi K, Iwasaki Y, Narukawa M, Iitsuka Y, Fukao T, Seki T, Ariga T, Watanabe T., 高須賀由佳, Koizumi K, 比江森美樹]
通讯作者:
比江森美樹
DOI:
10.1271/bbb.80751
发表时间:
2009-04
期刊:
Bioscience, Biotechnology, and Biochemistry
影响因子:
--
作者:
[Ayumi Kunimoto;Takako Sisino;K. Sakai;Tomoaki Matsumoto;Kyoko Takahashi;H. Yamashita;M. Hiemori;H. Tsuji;M. Kimoto]
通讯作者:
Ayumi Kunimoto;Takako Sisino;K. Sakai;Tomoaki Matsumoto;Kyoko Takahashi;H. Yamashita;M. Hiemori;H. Tsuji;M. Kimoto
Preparation and epitope mapping of a monoclonal antibody against Tri a Bd 27K, a wheat major allergen
小麦主要过敏原 Tri a Bd 27K 单克隆抗体的制备和表位作图
DOI:
--
发表时间:
2009
期刊:
Biosci.Biotechnol.Biochem. 73
影响因子:
--
作者:
[五十嵐喜治, 上原万里子, 長田恭一, 駒井三千夫, 八村敏志, 福島道弘, Ayumi Kunimoto, Yuki Kawakami, Nobuko Komiyama]
通讯作者:
Nobuko Komiyama
共 34 条
Development of purification method using fructose metabolic pathway of human iPS cell-derived hepatocytes
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The development of a new environmental communication model based on citizens' perceptions towards tidal flat restoration projects
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Stress modified nociceptive responses in the anterior cingulate neurons during estrous cycle in female rats
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Design of Nano Metal Catalysts Using Single-site Photocatalysts
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Design of Solid Base Catalysts from the Steal-Slag Materials
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Social Perception of Risks and Benefits of Tidal Flat Restoration Projects
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Design of Nano Metal Catalysts Using Single-site Photocatalysts
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依托单位:
Improvement of obesity and glucose tolerance by acetate
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批准号:18580128
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Condensation and photocatalytic degradation of environmental pollutants using hydrophobic mesoporous materials designed using F coating
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Design of Visible-Light Sensitive Titanium Oxide Photocatalyst and Degradation of Organic Pollutants
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负责人:YAMASHITA Hiromi
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依托单位:
海外基金