Regulation of ciliary beat frequency by sex hormones in ciliary cells of Fallopian tube.

采用高速摄像机（500Hz），用视频显微镜测量豚鼠卵巢周期内毛纤毛搏动频率（CBF）。适度增加雌激素浓度[βE_2]在排卵期维持高CBF(15.5Hz)，然后在排卵期进一步增加[βE_2]降低CBF（13.5 Hz）。在黄体前期和晚期，低[βE_2]和孕酮浓度[PRG]分别使CBF升高至17Hz和15Hz，在黄体中期，高[PRG]使CBF降低（~ 12Hz）。因此，豚鼠毛的脑血流受βE_2和PRG受体的信号控制。βE_2和PRG在CBf调节中相互拮抗，即βE_2抑制PRG的作用，而PRG则抑制βE_2的作用。

The ciliary beat frequency(CBF) of guinea pig fimbria during the ovarian cycle was measured by video microscopy using a high-speed camera(500Hz). A moderate increase in estrogen concentration, [βE_2], maintains a high CBF(15.5Hz) during the ovulation and then a further increase in [βE_2] decreases CBF(13.5 Hz) in the ovulatory phase. In the early and late luteal phase, low [βE_2] and progesterone concentration, [PRG], increase CBF to 17Hz and 15Hz, respectively, and in the middle luteal phase, a high [PRG] decreases CBF(～ 12Hz). Thus, the CBF of the fimbria was controlled by signals via βE_2 and PRG receptors in guinea pigs. Moreover both βE_2 and PRG antagonized each other in CBf regulation, that is βE_2 inhibits PRG actions and contrary, PRG inhibits βE_2 actions.