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Analysis of the mechanism of Aichi virus replication complex formation.

Analysis of the mechanism of Aichi virus replication complex formation.
爱知病毒复制复合体形成机制分析。
批准号:
21590514
负责人:
SASAKI Jun
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
Aichi virus is thought to be a causative agent of acute gastroenteritis in humans. Understanding the mechanism of the growth of pathogens is required for effective control of infectious diseases ; however, the mechanism of Aichi virus replication remains to be cleared. In this study, two host factors essential for Aichi virus replication were identified. The studies on other viruses report that these host proteins are involved in replication of the viruses. Findings in this study, together with the other studies, may lead to the development of drugs to control infection or growth of multiple viruses.
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A Golgi protein interacting with 2B, 2BC, 2C, 3A and 3AB is a host factor required for Aichi virus RNA replication
与 2B、2BC、2C、3A 和 3AB 相互作用的高尔基体蛋白是爱知病毒 RNA 复制所需的宿主因子
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Ishikawa K, Sasaki J, Maeno Y, Moriguchi K, Komoto S, Taniguchi K]
通讯作者: Taniguchi K
DOI: 10.1016/j.virusres.2009.10.009
发表时间: 2010-01-01
期刊: VIRUS RESEARCH
影响因子: 5
作者: [Ishikawa, Kumiko, Sasaki, Jun, Taniguchi, Koki]
通讯作者: Taniguchi, Koki
A Golgi protein interacting with 2B, 2BC, 2C, 3A and 3AB is a host factor required for Ai chi virus RNA replication
与 2B、2BC、2C、3A 和 3AB 相互作用的高尔基体蛋白是艾池病毒 RNA 复制所需的宿主因子
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Ishikawa K, Sasaki J, Maeno Y, Moriguchi K, Komoto S, Taniguchi K]
通讯作者: Taniguchi K
DOI: 10.1016/j.virusres.2011.12.013
发表时间: 2012-02
期刊: Virus research
影响因子: 5
作者: [J. Sasaki;Kumiko Ishikawa;K. Taniguchi]
通讯作者: J. Sasaki;Kumiko Ishikawa;K. Taniguchi
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