Analysis of the mechanism of Aichi virus replication complex formation.

爱知病毒被认为是人类急性胃肠炎的病原体。了解病原体的生长机制是有效控制传染病的必要条件；然而，爱知病毒的复制机制尚不清楚。在这项研究中，确定了爱知病毒复制所必需的两个宿主因子。对其他病毒的研究表明，这些宿主蛋白参与了病毒的复制。这项研究的发现，连同其他研究，可能会导致药物的发展，以控制感染或多种病毒的生长。

Aichi virus is thought to be a causative agent of acute gastroenteritis in humans. Understanding the mechanism of the growth of pathogens is required for effective control of infectious diseases ; however, the mechanism of Aichi virus replication remains to be cleared. In this study, two host factors essential for Aichi virus replication were identified. The studies on other viruses report that these host proteins are involved in replication of the viruses. Findings in this study, together with the other studies, may lead to the development of drugs to control infection or growth of multiple viruses.