Androgen receptor signaling in liver and pancreatic cancer
Androgen receptor signaling in liver and pancreatic cancer
批准号:
21590829
负责人:
KANDA Tatsuo
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
1)白细胞介素-6在胰腺癌细胞系中作为雄激素受体信号转导的正调节因子,提示白细胞介素-6和雄激素受体信号转导可能在胰腺癌发生过程中发挥重要作用。2)乙型肝炎病毒影响核受体及其相关信号转导。它们也可能参与乙肝病毒的复制和乙肝病毒相关的肝癌发生。
英文摘要
1)Interleukin-6 acts a positive regulator in androgen receptor signaling in pancreatic cancer cell lines, suggesting that interleukin-6 and androgen receptor signaling might play important roles in the progression of pancreatic carcinogenesis. 2) Hepatitis B virus affects nuclear receptors and their related signal transduction. They also might be involved in replication of hepatitis B virus and hepatitis B virus-related hepatocarcinogenesis.
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DOI:
10.1016/j.canlet.2011.07.025
发表时间:
2011-12
期刊:
Cancer letters
影响因子:
9.7
作者:
[Shuang Wu;T. Kanda;F. Imazeki;Shingo Nakamoto;H. Shirasawa;O. Yokosuka]
通讯作者:
Shuang Wu;T. Kanda;F. Imazeki;Shingo Nakamoto;H. Shirasawa;O. Yokosuka
Interaction of hepatitis C virus core and androgen signaling in hepatocarcinogenesis
丙型肝炎病毒核心与雄激素信号在肝癌发生中的相互作用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Moriwaki H, Shiraki M, Iwasa J, Terakura Y, T. Kanda]
通讯作者:
T. Kanda
DOI:
10.1089/vim.2010.0042
发表时间:
2010-10-01
期刊:
VIRAL IMMUNOLOGY
影响因子:
2.2
作者:
[Wu, Shuang, Kanda, Tatsuo, Yokosuka, Osamu]
通讯作者:
Yokosuka, Osamu
Quantification of hepatitis C amino acid substitutions 70 and 91 in core coding region by real-time amplification refractory mutation system reverse transcription-polymerase chain reaction
通过实时扩增耐药突变系统逆转录聚合酶链式反应对核心编码区丙型肝炎氨基酸取代70和91进行定量
DOI:
10.1080/00365520902937362
发表时间:
2009
期刊:
Scand. J. Gastroenterol
影响因子:
--
作者:
[S. Nakamoto, T. Kanda, Y. Yonemitsu, M. Arai, K. Fujiwara, K. Fukai, F. Kanai, F. Imazeki, O. Yokosuka]
通讯作者:
O. Yokosuka
膵臓癌におけるIL-6/STAT3/MAPK/ARシグナル活性と腫瘍進展効果の検討
胰腺癌中IL-6/STAT3/MAPK/AR信号活性及肿瘤进展效应的检测
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[沖津恒一郎, 神田達郎, 今関文夫, 米満裕, Chang C, 横須賀收]
通讯作者:
横須賀收
共 22 条
Sorafenib resistance and c-Jun in hepatocellular carcinoma
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批准号:17K09404
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2017
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负责人:KANDA Tatsuo
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依托单位:
Diversity of imatinib-resistance clones in gastrointestinal stromal tumors
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
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财政年份:2009
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负责人:KANDA Tatsuo
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Circulating cancer cells in patients with esophageal squamous cell carcinoma : A multicenter clinical trial
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批准号:17591381
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.48万
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财政年份:2005
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负责人:KANDA Tatsuo
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依托单位:
Sentinel lymph node in carcinoma of the thoracic esophagus
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批准号:13671287
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.28万
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财政年份:2001
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负责人:KANDA Tatsuo
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依托单位:
海外基金