Evaluation of assessment method of renal microcirculation dysfunction using pressure wire, Doppler guide wire and NO catheter.

点击翻译按钮获取中文摘要

The purpose of this study was to investigate whether renal flow reserve(RFR) and renal resistance index(RI) after percutaneous renal angioplasty(PTRA) correlate with renal function late after PTRA.RFR was defined as renal artery averaged peak velocity(APV) using a Doppler guide wire(FloWire, Volcano therapeutics, USA) during hyperemia divided by that at baseline. RI was calculated as the ratio of mean blood pressure to APV at hyperemia. The relationship between RFR and creatinine clearance(CCr), blood pressure, the number of anti-hypertensive drugs at follow-up was investigated.During follow-up, CCr, blood pressure, and the number of anti-hypertensive drugs did not change significantly. Ccr at follow-up was significantly higher in patients with high(>=1.9) RFR than low(<1.9) RFR.(41.2±15.3 vs. 49.6±12.9, p=0.045) Ccr at follow-up was higher in patients with low(<=2.7) RI than high(> 2.7) RI.(51.2±8.8 vs. 30.0±11.2, p=0.012)Renal flow reserve and renal resistance index immediately after PTRA may predict renal functional late after PTRA.