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Establishment of a simple differentiation diagnostic method of glucoprotein tumor markers by the pattern analysis in Western blotting

Establishment of a simple differentiation diagnostic method of glucoprotein tumor markers by the pattern analysis in Western blotting
Western blotting模式分析建立糖蛋白肿瘤标志物简易鉴别诊断方法
批准号:
21590981
负责人:
SATOH Hiroaki
金额:
$3.0万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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中文摘要
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英文摘要
It is not clear whether structures of glucoprotein tumor markers such carcinoembryonic antigen (CEA) and CA19-9 differ or not in various cancers. Western blot analysis of the expression patterns in various cancers was performed using original antibody against CEA which we made. The expression pattern of them was ladder bands pattern. In serum from lung, bands larger than 150kD were observed, but they were not in serum form other cancer patients and normal control (p=0.0352). Expression patterns were evaluated in such analysis using antibody against CA19-9 in sera from pancreas and colon cancers. A clue of simple differentiation diagnostic method of glucoprotein tumor markers by the pattern analysis in Western blotting was established.
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会议论文
泳動パターン解析による糖蛋白腫瘍マーカーの簡便な鑑別診断法の確立
利用迁移模式分析建立简单的糖蛋白肿瘤标志物鉴别诊断方法
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [佐藤浩昭, 他]
通讯作者:
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