Translational research for novel therapeutic strategy for skeletal dysplasias
Translational research for novel therapeutic strategy for skeletal dysplasias
批准号:
21591176
负责人:
YASODA Akihiro
金额:
$2.91万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
We performed the translational research of the CNP/GC-B system for impaired skeletal growth of skeletal dysplasias using mice model of skeletal dysplasias. We studied interactions between the CNP/GC-B system and molecules that play essential roles on endochondral bone growth using cell lines and organ culture system. Further we investigated the effects of the CNP GC-B system on impaired bone growth in mice models of skeletal dysplasias.
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DOI:
10.1210/en.2008-1676
发表时间:
2009-07-01
期刊:
ENDOCRINOLOGY
影响因子:
4.8
作者:
[Yasoda, Akihiro, Kitamura, Hidetomo, Nakao, Kazuwa]
通讯作者:
Nakao, Kazuwa
DOI:
--
发表时间:
2010
期刊:
Clin Calcium
影响因子:
--
作者:
[Yasoda A, Nakao K.]
通讯作者:
Nakao K.
Evaluation forthe role of serum c-type natriureticpeptide in endochondral ossification
血清C型利钠肽在软骨内骨化中的作用评价
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Toshihito Fujii, Yasato Komatsu, Akihiro Yasoda, et al]
通讯作者:
et al
DOI:
10.1210/en.2010-0078
发表时间:
2010-09-01
期刊:
ENDOCRINOLOGY
影响因子:
4.8
作者:
[Fujii, Toshihito, Komatsu, Yasato, Nakao, Kazuwa]
通讯作者:
Nakao, Kazuwa
Genetic basis for skeletal disease CNP therapy forachondroplasia
骨骼疾病的遗传基础 CNP 治疗软骨发育不全
DOI:
--
发表时间:
2010
期刊:
Clin Calcium
影响因子:
--
作者:
[Yasoda A, Nakao K]
通讯作者:
Nakao K
共 20 条
Translational Research of the CNP/GC-B system for Skeletal dysplasias
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批准号:19591075
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
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负责人:YASODA Akihiro
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依托单位:
Elucidation of molecular mechanism of endochondral ossification targeting novel therapeutic strategy for skeletal dysplasia
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批准号:17590959
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2005
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负责人:YASODA Akihiro
-
依托单位:
海外基金